For the explorative endpoint, RCB TILs were significantly predictive for response with OR = 0.56 (95% CI 0.40–0.78; p 0.0007) per 10% absolute increase in TILs and posttreatment Ki67 was borderline significant with OR 0.77 (CI 0.60–1.00; p = 0.05) per 10% increase in Ki67 index.
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For progression to NV, a similar effect of BMI for type 1 carriers versus noncarriers was not seen: the effect of BMI among carriers was not significant (OR = 0.6; 95% CI = 0.2, 1.9; P = 0.33), whereas it was borderline significant among noncarriers (OR = 1.2; 95% CI = 1.0, 1.4; P = 0.05).
Outcomes of LBBAP as CRT in LBBB vs Non-LBBB Pooled analysis from 2 studies showed a borderline significant difference in mean reduction of paced QRS duration (MD, 20.77 msec; 95% CI, −0.40 to 41.93 msec; P = 0.05; I 2 = 71%), and improvement in LVEF (MD, 6.00%; 95% CI, 0.15-11.84 %; P = 0.04; I 2 = 44%) in patients with underlying LBBB vs patients with underlying non-LBBB ( Fig. 4 ). 19 , 20 Quality assessment and publication bias Quality assessment of the individual studies determined that 8 of the included studies were of good quality with a low risk of bias.
Logistic regression analysis revealed borderline significant positive association between good outcome and time at a cooling depth (35°C–36.5°C, p=0.05); adjusted for old age, the association became significant (p=0.04).
A borderline significant positive association between MLR and AST was observed in the combined cohort (r = 0.188, p = 0.050).
There were borderline significant associations for SBP GRS ( β = −0.03, P = 0.05) and triglycerides GRS ( β = 0.03, P = 0.05), but none of these remained in sensitivity analyses excluding individuals with blood pressure-lowering treatment and lipid-lowering treatment, respectively.
Although sex was borderline significant ( p = 0.050), it is noteworthy that all three observed deaths occurred in female patients, and the limited number of events restricts the interpretability of this finding.
Therapy Adherence and Inhalation Technique Figure 5 A shows that, overall, both groups demonstrated a significant declining trend in adherence—significant in the control group ( P =.03) and borderline significant in the intervention group ( P =.05).
Evaluation of systemic markers of inflammation (hs-CRP, IL-6, IL-8 and fibrinogen) only revealed a borderline significant decrease in plasma hs-CRP concentration after doxycycline treatment (−0.51 μg/ml, P =0.050; Table 3 ).
Borderline significant associations were noted for CLL incidence and mortality (p = 0.050).
OS showed a borderline significant association with IGKC expression in Kaplan Meier analysis in ER positive carcinomas (Log-rank test: P = 0.050; Fig. 3D ).
A borderline significant reduction in the composite of HF hospitalization or cardiovascular death was seen with SGLT2 inhibitor use [HR: 0.80 (0.63–1.00); P = 0.05; I 2 = 29%].
Likewise, the fully adjusted association of hsCRP with CVD events was borderline significant when expressed per SD change (HR 1.16 (95% CI: 1.00–1.35), P = 0.05).
27.4 cm) than in the impaired development group, but this difference was only borderline significant ( P= 0.05) in this cohort.
There is also a borderline significant inter- action between birthweight and age at menarche (P = 0.05), with a stronger effect of birthweight in girls with earlier puberty.
There were no significant differences in LVEF, RVEF, native T1, native T2, extracellular volume, LV strain and myocardial scar between the COVID patients and healthy controls, although there was a borderline significant higher T1 in COVID patients (mean 1006 ± 31 ms vs 993 ± 29 ms, P = .05; Suppl.
Similarly, the 3rd quartile showed a borderline significant association (HR 1.386, 95% CI 0.999–1.924, p = 0.050).
The number of voxels representing high ΔSI (bolus) muscle values in infected rats, relative to corresponding controls at each time point, showed a steady decline as infection progressed (Linear regression analysis, borderline significant, P = 0.05).
The study compared “self-help decoupling” (authors stating that parts of decoupling may be considered a variant of HRT, as they both interfere at the motor level of functioning) with “self-help progressive muscle relaxation (PMR).” Using an intention to treat analysis, borderline significant advantage was found in favor of HRT in regards to hair pulling symptoms on the Massachusetts General Hospital-Hair-Pulling Scale (MGH-HPS) ( p = 0.05), with medium to strong effect size.
Repeated measures ANOVA (n=173) showed a borderline significant group by time by cognitive status interaction (F[1,169]=3.90, p =0.05, η p 2 =0.02), such that impaired persons in the probiotic group (M baseline =39, M follow-up =46) showed greater improvement in cognitive performance than impaired persons in the placebo group (M baseline =37, M follow-up =42), intact persons in the probiotic group (M baseline =53, M follow-up =54), and intact persons in the placebo group (M baseline =51, M follow-up =54).
Results showed no significant relations between mothers’ prenatal socioeconomic or social support adversity and offspring’s parasympathetic nervous system trajectories, but there was a statistically significant relationship between social support adversity and offspring’s heart rate trajectories (p<.05) and a borderline significant relationship between socioeconomic adversity and offspring’s sympathetic nervous system trajectories (p = .05).
Between-group comparison Table 3 displays a significant difference (P < 0.05) in groups for Stroop Color, RAVLT Hits, and borderline significant for COWA category and Stroop word; group∗ time interaction was significant (P < 0.05) for Stroop color and COWA consonant. 3 × 2 ANOVA shows that all the variables were matched at baseline between groups except Stroop Color, RAVLT average, Digit forward and backward.
After adjustment for sex, BSA remained a significant correlate of LVEDID, LVEDL and LVEDV (p<0.01 for all), and also remained a borderline significant correlate of LV mass (p<0.05), but was no longer a correlate of LV end-diastolic external diameter.
When all inflammation markers, significantly associated with breast cancer, were included together in the same model (model I) the risk estimates remained similar (i.e., the effects seemed to be independent of each other), but the association was only borderline significant for IL-1β (p = 0.05).
This yielded an AUC.64 for concentration, which was borderline significant ( p =.05).