“borderline significant”

In support of COX11 and TOM1L1 being the targets of this breast cancer susceptibility locus, eQTL analyses in normal breast tissue showed borderline significant associations of the risk alleles of top candidate causal SNP rs2787486 with increased expression levels of both TOM1L1 and COX11 ; candidate SNP rs2787481 also showed evidence of allelic imbalance in COX11 expression.

Most findings remained significant or borderline significant in this restricted data set (Figs.

Next, we looked at tryptophan metabolism in macrophage subtypes, as it was borderline significant in our analysis and is a well-known metabolic pathway in macrophages ( 65 , 67 , 68 ).

However, the Central region remained borderline significant.

The inverse association observed between adherence to the WCRF/AICR Score and advanced precancerous lesions remained significant for all modifications of the score, except when subtracting the alcohol component, where a borderline significant association was observed.

One meta-analysis of Wang et al., including six studies with 2727 patients, reported a borderline significant increase (RR: 1.20, 95% CI: 1.00–1.44) in the likelihood of receiving a kidney transplant among patients treated with HDF compared to those patients treated with HD [ 10 ].

The following registered factors were borderline significant, namely: a history of heart failure; increased systolic blood pressure; and currently taking antihypertensive drugs now, versus previously.

The significance level was set at p < 0.05, while p -values between 0.05 and 0.1 were considered as borderline significant.

For case NIPT-67 (cervical cancer), we found a borderline significant CNV gain of chromosome band 3q26 which did not meet the Maastricht criteria for ‘malignancy-suspicious’, but is a known hallmark of squamous cervical carcinomas ( Supplemental Table S2 ). 16 Time between NIPT and cancer diagnosis and symptoms of disease The mean time between the NIPT and the diagnosis of pregnancy-associated cancer was statistically significantly shorter for the group with a malignancy suspicious-NIPT result when compared with the group with a non-suspicious NIPT result, respectively 49.9 days (± SD 31.8) and 100.7 days (± SD 74.9), p = 0.001 ( Fig. 3 ).

The At risk class only had borderline significant scores in the PF domain (− 1.01 (− 2.05; − 0.03)), compared to the reference class.

For both outcomes of interest, the difference in satisfaction between intervention and control arms was at least borderline significant at each cutoff, e.g., very satisfied, satisfied, neutral, and dissatisfied (Table 2 ).

Only in the Luminal group, a borderline significant difference in AUC between the subtype specific and non-subtype specific predictor was observed (corrected p-value: 0.0709).

In the analysis of plaques percentage, the two-way interaction of diameter and antibody was statistically significant, and the overall interaction term was borderline significant; therefore, the final model selected included all three two-way interaction terms.

Finally, a meta-analysis of 70 studies comprising 41,534 subjects, mainly derived from community-based or hospital-based populations with low-to-intermediate pretest CAD probability, showed that EAT volume was independently associated with obstructive CAD (coronary stenosis and myocardial ischemia) and CAD events, whereas the correlation with CAC was only borderline significant [ 69 ].

Similarly, analyses of PF subgroups were largely null, with only a borderline significant association observed for high bread consumption.

The interaction term between ACEI/ARB and LVEF ( P =0.307) for mortality was not significant, whereas that for ACEI/ARB and ATTR risk model ( P =0.054) for mortality was borderline significant.

However, the 3′ UTR CALU SNP rs11653, the non-synonymous rs2307040 and the two intronic rs339054 and rs1006023 gave borderline significant P -values (Table 1 ).

Also, in these subgroup analyses, no variables were significantly associated with development of knee OA, except for borderline significant results for morning stiffness.

The borderline significant associations between Ability and country with AMU were included as well.

In week 8 mean BLA after canter1 was significantly lower 2.4 ± 0.5 mmol/L in SET A and 1.7 ± 0.8 mmol/L in SET B (borderline significant).

It should be noted that the finding was borderline significant (p 0.048) and in presence of a confounder (initial BMI).

We observed a statistically significant difference in serum non-HDL cholesterol concentration and a borderline significant difference in total cholesterol concentration from two to 20 years of age between those who had been breastfed for 4–6 months compared with their peers breastfed for 6–9 months.

The only borderline significant difference was the presence of microalbuminuria, which was observed in more patients with LGE.

In contrast, the relative abundance of Bacteroidota , which decreased in both the OB and BPA-exposed groups (NW10, OB10), was borderline significant in the larger sample analysis ( Figure 7 g).

Interestingly, the 2R3R-TS gene was also borderline significant at week 7 for an effect of TSI on occurrence of genotype.