For women, there was a borderline significant positive association between gender inequality and double burden of disease (OR 1.05, 95% CI 1.00 to 1.11, p=0.06), while there was no association in men (OR 0.99, 95% CI 0.95 to 1.04, p=0.75).
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For the SN, there was a stronger interaction ( b = −0.03, SE = 0.01, t [89.6] = −3.47, p < 0.001) due to a borderline significant increase in contrast with age in HC ( b = 0.04, SE = 0.02, t [26] = 1.93, p = 0.06) and a significant decrease in AD ( b = −0.03, SE = 0.01, t [69.9] = −3.17, p = 0.002).
The risk of infant mortality was 1.54 higher than in the rest of the metropolitan area, the log likelihood ratio reduced from 12 to 8.74 and the cluster of infant mortality became borderline significant (p=0.06), indicating that the socioeconomic index explained a major part of the excess infant mortality shown by the unadjusted analysis [ 46 ].
Inhibition of Mef2a led to significant downregulation of 14q32 microRNA miR-329 ( Figure 6 A; p = 0.0026) and a borderline significant downregulation of miR-494 ( Figure 6 B; p = 0.06).
colonization subgroup analysis revealed the pooled estimates of 51% (95% CI: 0.46–0.57) with I2= 98.7%, for clinical and 39% (95% CI: 0.27–0.52) with I2= 94.5%, for colonization studies, with a borderline significant variation ( p = 0.06), which suggested a trend toward significant that should be confirmed with further studies.
A borderline significant result was found for search engines (58% vs 51%, p = 0.060) and official webpages of health services or health organizations (16% vs. 11%, p = 0.062).
In the model of poor RBC storage quality (i.e., FVB), DLA was associated with a borderline significant improvement in 24-h PTR using fresh blood ( p = 0.06) and a statistically significant improved PTR after 6-day of storage ( p < 0.001; Figure 8C ).
A 24-month survival analysis in these herds found that ELISA-positive cattle faced a borderline significant ( P = 0.06) 18% greater hazard of being culled compared to their ELISA-negative herdmates.
Paired t -Student revealed no significant differences regarding the first and the second evaluation, or between the second and the third measurements, except for a small borderline significant increase in TT (combined first and second and second and third evaluations—377 ± 141 ng/dL vs. 393 ± 138 ng/dL, t = 1.990, p < 0.06).
However, the CVI showed a mild negative correlation that was borderline significant (Pearson correlation coefficient = − 0.36; p = 0.06).
In parathyroid tissue there were no difference between PH and SH for p53, Ki-67, caspase, EGFR expressions; while there were significantly difference for TGFα ( P = 0.047) and borderline significant difference for p21 ( P = 0.06) expressions.
Among men, the unadjusted logistic regression analyses showed significant associations between BMI category and case status for all SCL-90 subscales except anxiety which was only borderline significant ( p = 0.060).
There was a weak positive correlation between storage time and NfL levels ( ρ = 0.14, p = 0.02) and a weak, borderline significant correlation with p‐tau217 levels ( ρ = 0.11, p = 0.06), as shown in Figure S2 .
There was a borderline significant dose–response in MSLN expression between these two doses ( P = 0.06), whereas no statistically significant difference was observed between the 12 Gy and 16 Gy doses ( SI Appendix , Fig.
We observed a statistically significant genotype-by-sex interaction for MDM4 rs4245739 ( p = 0.01) and a borderline significant interaction for rs1563828 ( p = 0.06).
There were significant associations with gender (males have a higher risk than females: RR = 6.8, P = 0.002) and age (for each decade older, the risk increases by a factor of 1.9, P <0·001), and there was a borderline significant association with tuberculin skin test positivity (RR = 6.84, P = 0·06).
The sixth CpG site (CpG 212 at chr8: 128753145) displayed a similar pattern, with a borderline significant p -value ( p = 0.06).
In cohort-2, DFS and BCSS was borderline significant (DFS: log rank = 0.06, BCSS: log rank p = 0.06; S3 Fig ), while in TCGA there was no association ( S3 Fig ).
A borderline significant reduction in ANP (43.5 vs. 31.7 pg/ml, p = 0.06) may suggest a decrease in cardiac filling pressures with PDEVI and BNP.
Although this was only borderline significant ( P = 0.06) in this small patient group, the feasibility of sorafenib drug monitoring to achieve a target exposure supports this strategy to improve controlled drug exposure.
A borderline significant protective effect of aspirin® was further observed: 49 patients (22%) in the PE negative group vs. 24 (15%) in the PE confirmed subgroup ( p < 0.06).
The association of HbA1c and subclinical atherosclerosis was borderline significant (OR: 2.17, 95% CI: 0.98–4.85, p value = 0.06) in women (data not shown).
Heading was significantly associated with poorer performance on psychomotor speed ( p < 0.001) and attention ( p = 0.02) tasks and was borderline significant with poorer performance on the working memory ( p = 0.06) task.
In a multivariate model including cN-stage ( P = NS) and HR status (HR: 0.42, 95%CI: 0.22–0.79, P = .007), the NLR remained borderline significant (HR: 0.51, 95%CI: 0.26–1.02, P = .060). 4 Discussion In this study, we investigated commonly used peripheral inflammation markers (NLR, PLR and LMR) in a cohort of 127 IBC patients (of which 34 patients had metastatic disease).
Low positive affect had a weaker, but still statistically significant association with problems with self-care (OR: 5.12; 95% CI: 1.48–17.77; P = .01) and usual activities (OR: 1.94; 95% CI: 1.26–2.98; P = .002); the association with anxiety/depression problems was borderline significant (OR: 1.54; 95% CI: .99–2.39; P = .06), showing that a high score on positive affect was protective of these problems.