“borderline significance”

TPOAbs had a borderline significance by age groups in the AS group ( p = 0.06) and did not statistically significant vary in the non-AS group ( p = 0.602).

Both MPNSTs with methylated and unmethylated RASSF1A promoter had lower expression than the benign neurofibromas ( P = .0001 and P = .05, respectively), suggesting that additional mechanisms are involved in silencing the RASSF1A gene in MPNST. For the MPNSTs, a borderline significance was seen with the second assay, between promoter hypermethylation and reduced gene expression ( P = .06; data not shown).

In the multivariable analyses, IDH and SH were associated with impaired LVGLS [adjusted odds ratio (OR) 2.69 and 2.66, P < 0.001], and borderline significance was observed for elevated BP (adjusted OR 1.90, P = 0.060); there was no significant association between any of the BP groups and LVGCS.

80%, p = 0.05) and previous HPE had borderline significance (100% vs. 83%, p = 0.06)—Table 3 .

Similarly, multivariable analysis that included all eight risk variables used in DIPSS-plus disclosed significant predictive value for all except constitutional symptoms ( P =0.9) and leukocyte count >25 × 10(9)/l with borderline significance ( P =0.06).

Borderline significance was found for global functioning (CIBIC-plus score; p = 0.06).

After dichotomizing by median of CD8 IHC results, no association was found between pre-CCRT CD8 level and patients’ survival (Log rank test, p = 0.268 in Figure 3 C and HR = 0.66, 95% CI = 0.18–2.35, p = 0.52 in Table 4 ); however, there was borderline significance for those with lower post-CCRT CD8 level to have a longer survival period (Log rank test, p = 0.06, Figure 3 D and HR = 4.89, 95% CI = 0.96–24.92, p = 0.06, Table 4 ).

A study among Brazilian-Latino patients also suggested borderline significance ( P = 0.06).

A Fisher exact test was, therefore, made to calculate the relationship with NAFLD, achieving borderline significance ( p = 0.06) in the recessive model.

We observed a borderline significance of SERPINA6 expression among the CC, CG and GG genotype carriers (Kruskal-Wallis one-way ANOVA test: P = 0.060).

RT-qPCR confirmed induction of NOTCH/TGF‐β‐pathway genes ( NOTCH1 , HES1 , TGFB2 , TGFBR2 , and ID3 ) and reduction of ASCL1 and DLL3 , with some markers showing borderline significance (e.g., TGFBR2 P = 0.06) (Fig. 9j and Supplementary Fig. 18h, l ).

Patient characteristics were similar across pathways, although P3 had a statistically significantly higher mean age (p = 0.005), P2 had more days since operation (p = < 0.001), and P1 had less travel time, although only at borderline significance (p = 0.06).

In 12,654 patients from seven studies where multiple anticancer agents were used in the procedures, TACE was associated with a 25% reduction in hazard of death (HR = 0.75, 95% CI = 0.64–0.88, p = 0.0004), while in 436 patients from three studies that only used one anticancer agent, the reduction associated with TACE was smaller and of only borderline significance (HR = 0.83, 97% CI = 0.68–1.01, p = 0.06) but showed higher homogeneity ( I 2 = 0, p for heterogeneity = 0.66).

Notably, the IMRT arm showed higher local control, despite having a larger clinical target volume (i.e., the target volume of which is planned to receive the prescribed dose with borderline significance, mean 439 vs. 294 cc, p = 0.06) ( Supplementary Table S2 ).

When evaluated in the multivariate logistic regression analysis only CCI had a borderline significance ( p = 0.06).

Moreover, our analysis of obesity for rs6013029 showed borderline significance ( p = 0.06) with a 1.13-fold per allele increase in the risk of developing obesity.

The CRP had borderline significance for prediction of serum OGL results ( p = 0.060).

Moreover, in p-AKT high GCB-DLBCL, loss of nuclear PTEN expression was associated with poorer PFS with borderline significance ( P = .06, Figure 2 B ), although it was associated with significantly lower mean levels of antiapoptotic Bcl-2 ( P = .0068) and MDM2 ( P = .0011) expression.

The difference between CFRs for classic respiratory diphtheria in Latvia and the member countries excluding Latvia (12% and 24%, respectively) showed borderline significance (p = 0.06).

Low MASP-2 levels were also correlated with high MASP-3 levels, again only in MS patients with active disease, but with borderline significance (Spearman's r = −0.401, P = 0.06).

Comparing frequencies of different NK cell subsets, the results revealed a borderline significance in the lower percentage of conventional cytotoxic NK cells with CD3 − CD56 dim CD16 + phenotype (9.88 ± 1.30 vs. 12.44 ± 1.49, p = .06) and a higher percentage of tolerant NK cells with CD3 − CD56 + CD27 − CD11b − phenotype (0.82 ± 0.13, 0.48 ± 0.10, p = .06) in peripheral blood of the patients compared to the HDs.

An increment in the continuous z-score for triglyceride levels, however, was associated with increased male hip fracture risk at borderline significance (HR 1.13, 95%-CI: 1.00–1.29, p = 0.06 in the adjusted model, Table 4 ), in particular in men aged >50 years (HR 1.15, 95%-CI: 1.00–1.32, p = 0.05, Table 5 ).

These associations reached statistical significance in one group (Spearman correlation, rho = –0.234, p = 0.04) and borderline significance in the other (Spearman correlation, rho = –0.199, p = 0.06).

Primary endpoint The meta-analysis of pooled hazard ratios in all trials, including a total of 1789 patients, showed that all-cause mortality in the ICD group decreased with borderline significance (167 of 886 patients, i.e. 19%) in comparison to optimal pharmacological treatment (195 of 895 patients, i.e. 22%), with a HR of 0.48 (95% CI 0.67–0.10); p = 0.06; heterogeneity p = 0.78; I 2 = 0% ( Fig. 2 ).

Adjustment for statin use minimally affected the comparisons between plasma lipids in AD patients and controls, except for a shift to borderline significance for LDL-cholesterol (from p = 0.06 to p = 0.04) and an opposite shift for CER (from p = 0.02 to p = 0.12).