The Methods section could provide clearer justification for variable selection and categorization, and some statistical interpretations (e.g., borderline significance) should be stated cautiously.
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“borderline significance”
In the literature
Nonetheless, albeit reaching borderline significance in the adjusted analysis, physical activity contributed to BP control.
Non-timing errors (‘omission’ and ‘other’ errors) reduced from 51 (4.77%) to 11 (2.55%), a reduction of 46.5%, which had borderline significance at the 5% level, although this was lost after adjusting for confounders.
Of note, low expression of PTEN or INPP4B (below median H ‐score value) and mutations in the PIK3CA/AKT/mTOR pathway were associated with higher expression of p4EBP1 or pS6 with borderline significance (data not shown).
In patients with LDL-C<3 mmol/L, fibrates use was associated with 66% risk reduction of CVD with borderline significance.
Our finding (p = 0.012), therefore, showed borderline significance, being slightly higher than the significance level.
In the CRC-nm group, Lactobacillus crispatus showed negative correlations with several amino acid-related metabolites, including L-phenylalanine, L-methionine, and L-tyrosine, whereas its correlation with sarcosine showed borderline significance after adjustment.
Both applications highlight the need for larger validation cohorts to address statistical uncertainties—particularly regarding the borderline significance of the multimodal model—and to clarify its potential benefits in reducing diagnostic errors, patient anxiety, and healthcare costs through improved specificity.
In the sensitivity analysis restricted to the subgroup of patients that did not receive CMV antiviral prophylaxis ( n = 125), the development during the first 90 days of CMV infection at any level (adjusted HR: 2.54; 95% CI: 1.09–5.90; p -value = 0.030) or high-level viremia (adjusted HR: 2.37; 95% CI: 1.14–4.95; p -value = 0.021) was associated with subsequent non-CMV infection, with borderline significance.
T-values ≥ 60 indicate borderline significance, T ≥ 64 indicates significant clinical relevance.
In our own series, although plasma PTH levels were higher in male patients, only a borderline significance was found between sexes in terms of PTH-WO values.
( 57 ) Higher intake of long chain menaquinones was associated with lower CHD mortality with borderline significance ( p for trend = 0.06), HR 10 μg being 0.86 (95% CI: 0.74, 1.00) in the prospective cohort study including 33,289 participants aged 20–70 years 95% at baseline.
Although statistical corrections for multiple comparisons (eg, Bonferroni adjustment) could be applied in future analyses, our findings should be interpreted with caution, particularly where interaction effects showed borderline significance.
Differential abundance analyses yielded multiple differences with borderline significance between IBS and HCs after false-discovery rate correction (Wilcoxon rank-sum test, q < 0.10).
These results, supported by the borderline significance of differences between control groups in the morphological measures of Experiment 2 (reported above), lead us to believe there are other strong influences within the growing bed masking the affects of the mechanical stress induction.
However, owing to borderline significance levels, the limited number of included studies, and serious inconsistency in evidence, these findings should be interpreted cautiously.
Additionally, there was borderline significance between hearing problems alone and tinnitus alone at phase two and probable CMD at phase three (AOR = 1.35, 95% CI 0.99–1.85 and AOR = 1.35, 95% CI 0.99–1.84, respectively).
In terms of OS (Figure 3A ), osimertinib (HR, 0.90; 95% CrI 0.83 to 0.99) and lazertinib (HR, 0.89; 95% CrI 0.79–1.00) demonstrated significant improvements compared to first‐gen TKIs, though the upper bounds approach 1, indicating borderline significance.
Compared to normal sodium levels, hyponatremia was significantly associated with lower CERAD WLT-IR (β = -0.34, SE = 0.15, p-value 0.035) and CERAD WLT-DR scores (β -0.48, SE = 0.10, p-value < 0.001) and showed borderline significance with AFT scores (β = = -0.38, SE = 0.19, p-value 0.052).
describe a borderline significance of TPA DD/PAI-1 4G4G genotype combination for reduced risk for MS Slovenian and Croatian patients [ 18 ].
SDNN was negatively associated with all inflammatory biomarkers, although the relationship with the lymphocyte cell count was weakest and reached only borderline significance.
As for serum cTnI, only a borderline significance was demonstrated ( Table 3 ).
In addition, we found a borderline significance of the prognostic value of sex in CLL patients with the tendency of females to survive better than in males.
Using the KS, the difference in the performance between the three residents (AUC 0.842–0.928, p = 0.03, p > 0.08, respectively; Table 2 ) varied between significance and borderline significance.
Asthma control and lung function The results indicated that C-ACT scores showed a trend towards improvement after 12 weeks (borderline significance).