In a study 2742 Turkish adults prospectively evaluated for more than 7 years revealed that current cigarette smoking played a protective role at borderline significance but former smokers uniformly exhibited significantly higher risk for the development of hypertension.
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“borderline significance”
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However, c-AJCC stage had borderline significance ( Table S3 ).
The LAIV VE showed evidence of significant VE against laboratory-confirmed influenza B infection, borderline significance against influenza A(H3N2) and moderate, non-significant effectiveness against influenza A(H1N1)pdm09.
Furthermore, in PD-L1 positive lesions, three genes ( CD27 , CD6 , IL10) were significantly upregulated (p<0.01), while two others were down-regulated (LCK and TLR8, showing borderline significance).
Although the correlations detailed in Table 3 (at the level of a cluster extent threshold of K E ≥100) do not cover all of the regions in which the RMTLE and LMTLE patients differed, we identified that, at borderline significance, GMV reductions in the middle frontal gyrus [ K E =91, coordinates=(39,48,12), p FDR =0.020] and temporal subgyral [ K E =55, coordinates=(47,-4,-18), p FDR =0.027] areas were negatively correlated with the duration of epilepsy and seizure frequency, respectively.
After evaluating each feature in a univariate Cox model from the validation set, two radiomic features reached significance or borderline significance ( Figure 6B and Table 4 ).
However, the differences (although borderline significance) in attitude scores would, nevertheless, infer that WPV-PMTP is effective.
Interestingly, female C57BL/6N mice showed better motor function in the rotarod test compared to males with borderline significance in trial 2 and significant difference in trial 3 (Supplementary Fig. 3 ; Supplementary Table 2 ).
However, as the age increases, subjects with age 40–64 showed borderline significance (95% CI, 1.00–2.24) and the subjects with age greater than 65 having a higher prevalence of dementia showed statistical significance.
We were able to detect increased BCAA levels in daf-2 homogenates, albeit with only borderline significance ( Fig. 5 F ).
Although no genes identified by us were significantly confirmed by the WTCCCHS data (Caucasian), COMMD7 , which encodes COMM domain-containing protein 7 on 20q11.21, was replicated with a borderline significance (pFDR LRC = 7.46×10 −2 ).
In contrast, the evidence for UIE, cardiac T2* MRI, RVEF, and all-cause mortality was rated as low, primarily due to imprecision, limited number of included studies, and borderline significance in effect estimates.
ELN low risk was significantly associated with survival after ICU discharge, whereas ELN high risk exhibited only borderline significance.
In the JSPH cohort, the mutation frequencies of FAT4 ( P = 0.052) and KMT2D ( P = 0.058) were higher in DEL patients with borderline significance in the MCD subtype (Figure 2D ), and in the OTHER subtype, CD83 exhibited a higher mutation frequency in DEL patients (33.3%) than in non‐DEL patients (2.0%), but there were few DEL patients of the EZB subtype in the JSPH cohort for further mutation analysis.
Although IL-10 shows a positive trend, its borderline significance hints at a potential protective effect that may not be fully captured in this model.
Several trends that were highly statistically significant on estimation of the raw odds ratio were now absent or of only borderline significance.
The pANCA−/ASCA− pattern was observed less often in active UC when compared to remission phase although with borderline significance ( 9 ).
According to a previous Ecotyper study in publicly available DLBCL cohorts by Steen et al., 37 the LE4 ecotype was characterized by a higher abundance of immune reactive T cells and was associated with the ABC subtype and unfavorable OS with borderline significance; CD4 T-cell state S2 and neutrophil state S1 had significant associations with unfavorable prognosis.
Theories Regarding the Biological Link between DM and OvCa Most previous epidemiological studies [ 39 , 40 , 41 ] report no increased risk of OvCa among patients with DM; but some show a borderline significance of associated risk [ 42 ].
After inclusion of rheumatoid factor and BL erosions in multivariate logistic regression analyses, however, the MBDA score at BL, but not DAS28-CRP, achieved borderline significance. 33 In our previous study based on this trial, we demonstrated the independent predictive ability of the MBDA score at BL for subsequent 1 year RRP. 25 This result posed a question concerning the role of the MBDA score in patients with RA whose disease (and MBDA score) is already affected by treatment.
Nevertheless, we recommend cautious interpretation of associations with borderline significance.
APR was associated with a higher rate of total septic complications than LAR (OR = 2.38, 95% CI, 0.96–5.91; P ≈ 0.06), indicating borderline significance.
Only the XPC rs2228000 TT genotype (HR = 1.81, 95% CI = 0.99–3.29, p = 0.053) showed an increased risk of poor OS at borderline significance compared with the CC+CT genotypes.
The tumor status (clinically recurrent versus primary) had also an impact on disease-specific survival in univariate and with borderline significance in multivariate analysis, which is similar to data from series of liposarcomas from the National Cancer Institute, Milan, Italy [ 9 ].
In addition, p value of TRPV4 low expression in bladder cancer and respond to immunotherapy was close to 0.05, had borderline significance.