Although after adjusting for OA, the observed association between P1NP and JR risk was attenuated to borderline significance, likely reflecting shared variance, as OA progression involves bone remodelling processes captured by P1NP.
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“borderline significance”
In the literature
Another study in Kenya showed that chronically ill had, despite having a borderline significance, 22% greater odds of coverage compared to those without a chronic disease [ 63 ].
Community state distances to the center of CST IV-A for the N-9 and CS groups were significantly different from those for the placebo group at visit V4 and showed borderline significance at visit 5 ( Fig. 4 ).
However, SNPs with borderline significance not meeting the genome-wide threshold may still be associated with disease, 16 , 19 thus a PRS may improve the estimate of the “true” genetic risk and predictive power by including a larger number of SNPs using more lenient statistical thresholds. 18 To account for correlated and coinherited SNPs (
The statistical significance level was set at 0.05, additionally, the borderline significance level at 0.1 and the tendency at 0.2 for all analyses.
The borderline significance between ischemic stroke and control groups regarding a new diagnosis of ≥30‐s‐long AF episodes on Holter monitoring is probably a reflection of the fact that various tools such as ECG or inpatient rhythm monitoring capture new AF episodes in many stroke patients and thereby lead to an inevitable drop in the yield of Holter monitoring among ischemic stroke patients in this regard.
Associations with other parameters Earlier disease onset characterized those T1DM individuals who did not carry any A allele of the rs3087243 polymorphism compared to A allele carriers with borderline significance (individuals with rs3087243- G/G genotype: 15.8 years [95% CI: 11.98-19.62] vs.
Unlike ΔGH IO , ΔGH OS was different between responders and non-responders with borderline significance during the entire test time ( Fig. 4 ).
ICS/LABA reduced adverse effects rates versus FF/VIL/UMEC (RR = 1.07, 95%CI = 1.01 to 1.14) and BUD/FOR/GLY (RR = 1.05, 95%CI = 1.00 to 1.11) with borderline significance.
Lastly, the associations between the BARS measures and the 5-NM composite score demonstrated borderline significance for CPT latency, MTS latency, and MTS count score ( Supplementary Table S4 ).
As per rectal cancer, a previous study discovered that there was an increased risk with borderline significance [ 12 ].
This study presents some limitations: Firstly, the low prevalence obtained may have limited the identification of other possible predictors of infection and may explain the borderline significance of the risk factors associated with infection.
Striatum tissues presented with borderline significance of differences for several miRNAs (Table S5 , Fig.
plantarum and a decrease in Actinobacteria , both of whose changes in abundance were correlated with changes in visceral adiposity, with borderline significance.
In NHL, we found that patients with high expression of CCDC91 had poor survival, with borderline significance 16 .
Former smokers were at a higher risk of SL due to cancer at a borderline significance level (HR = 1.38, 95% CI = 0.99 to 1.92).
Peak heart rate is associated with greater ET, with borderline significance.
Over all, no clear relationship between religion and ethnicity on decision making on engaging in sexual intercourse and condom use was found, except that women with no religion (OR = 0.52) were less likely to make decision on engaging in sexual intercourse compared to those of the Catholic faith while women of the Islamic faith were more likely to make decision regarding condom use, although at borderline significance.
This threshold was chosen to capture not only statistically significant variables but also those with borderline significance, which may have clinical relevance.
Conversely, HDW, which was not initially highlighted, emerged as significant in this adjusted dataset, suggesting borderline significance for certain variables.
Furthermore, the negative findings for an association between the δMIR and the HDI, CHE per capita, and CHE/GDP with CHE/GDP that presents a borderline significance were also established.
By using Real-Time PCR, the mRNA expression of CYP1A did not show any differences between males and females from each site, but it was at borderline significance level.
During a 10-year follow-up along with such predictors of death as female sex, diabetes mellitus, and multifocal atherosclerosis, the borderline significance of the pathological CAVI was also noted.
We acknowledge the limitations of our study, particularly the relatively small sample size and the borderline significance of the results, which may affect the reliability and generalizability of our findings.
However, these modifications were observed only sporadically and in low intensity and borderline significance and were therefore excluded from the final search.