“borderline significance”

The higher risk of irTAEs for females is likely to be due to a preponderance of autoimmune diseases in females compared to males [ 15 ] and the borderline significance of younger age as an independent risk factor for irTAE in unknown, but it has been suggested that it could at least partly be explained by relationship between thyroid diseases and younger women [ 15 ].

A p value between 0.05 and 0.1 was considered to indicate borderline significance.

The transgenic T1 kernels from four (OmtA-6, 7, 10, and 12) out of the five events exhibited lower mean aflatoxin production than those without the omtA transgene, although the difference is not statistically significant except for OmtA-7 and OmtA-12, which were at borderline significance with p -values ranging from 0.056 to 0.063 ( Table S1 ).

Having 3 or more children was protective against elevated BP with a borderline significance in univariate analysis, but this protective effect disappeared when other factors were taken into consideration in the multivariate analysis.

Variables such as BMI and comorbidities demonstrated limited or borderline significance, underscoring the multifactorial nature of outcomes in this patient population.

The associations between the non- APOE PRSs and plasma p-tau181 within Aβ positives could, however, only be seen (at borderline significance level) in individuals with MCI.

Natives from the Maghreb (Maghrebins) showed considerable gender discordance, with men having both a higher prevalence (borderline significance) and a reversed gradient and women having lower prevalence than the reference population.

We added HBA1C to the final model and found that elevated HbA1c levels reduced the odds of low BMD with borderline significance (OR: 0.746 95% CI 0.557–1.00, p- value 0.05).

We did not find correlations between other genetic alterations and neoantigen load, although this analysis (including the borderline significance for the MYC amplification and the PIK3CA mutations) was limited by the small number of tumors that harbored these genetic alterations.

In multivariate analysis, after allowing for stage, Bid expression was a significant prognostic factor for both disease-specific and metastasis-free survival, and had borderline significance for recurrence-free survival ( Table 3 ).

Similar to the results of shoulder function, there were no statistically significant differences between the treatment groups in QoL at 1 year after surgery (both ITT and PP analysis), although borderline significance was observed at 6 weeks in EQ-5D index scores and 6 weeks and 12 months in EQ-5D VAS scores (PP analysis).

In region D2, all three methods (FBAT, GEE and GRE) indicated marker B03T3056 had borderline significance with a p -value of around 0.01 (Figure 1 ).

The results showed that heavy consumption versus a lower level of consumption was associated with, in excess of a twofold increased risk of preterm (<37 weeks) delivery, with a borderline significance.

This reduction resulted in borderline significance in intermediate-risk patients.

Over the entire study period, Black patients with high TMEM doorway score had higher odds of distant recurrence compared to those with low TMEM doorway scores (OR 3.24, 95% CI 0.97–12.49, p = 0.07), with borderline significance (Fig. 4b ).

On d0, these correlations had only borderline significance on both Chr13 and ChrX.

A borderline significance existed in body mass index (BMI) among the three groups.

Hypertension decreased 20% between both studies with borderline significance (Model A= OR: 0.82 [95% CI: 0.64–1.04]; Model B= 0.79 [0.62–1.02]).

We also identified a possible association between GSTM1 null polymorphism and prostate cancer biochemical recurrence risk with borderline significance (HR = 1.29, 95%CI = 0.97–1.71).

The findings demonstrated that specific polymorphisms in ATM (G60A) and CHK1 (G35A) were significantly associated with OS, whereas the ATR C340T variant showed borderline significance.

We expect that variant-specific priors will also be useful to better understand colocalisations of interest, such as colocalisations that show borderline significance.

The difference between PE and healthy controls was significant, whereas PIH and controls differed only with borderline significance, possibly due to the small (pilot) study size.

CD163, a marker of the innate immune system showed borderline significance, indicating that further studies investigating predictive capacity of the innate immune system are warranted.

Predictors of increase in bone turnover markers At univariate analysis we found significant associations of greater OPG Δ [wk 48-bl] with higher CD4+/CD8+ T-cell ratio (r 2 = 0.06, p = 0.03), and with greater eGFR estimated by CKD-EPI based on cystatin C values at baseline (r 2 = 0.06, p = 0.03), but only the latter maintained a borderline significance at multivariable model (Table 2 ), indicating that there was a greater increase in OPG (mean: 0.21 ng/mL) in patients with better renal function at baseline.

C2 was associated with a higher asthma symptom score (adjusted mean score ratio (aMSR) [95% confidence interval] = 1.22 [0.98; 1.53]) at borderline significance.