In contrast, the borderline significance of unweighted UniFrac suggests these differences may be primarily driven by the changes in abundance rather than the presence or absence of specific taxa.
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“borderline significance”
In the literature
In contrast, in men, age showed borderline significance in Model 1 (pFDR = 0.065), which was consolidated in Model 2 (β = −0.38; pFDR = 0.044).
Key risk factors included pre-pregnancy overweight/obesity (OR 1.9, CI: [1.2–3.2]), and a borderline significance for the first-early second trimester BMI (OR 1.5, CI [0.9–2.3]).
Of note—though we found only a borderline significance potentially due to the limited sample size in our study—PCOS women were only half as likely to be equol producers than healthy women ( Figure 2 B).
Reclassification analyses, based on the FT3 cutoff, showed modest incremental values, with significant improvement at the 25th percentile risk threshold (NRI = 0.032, p = 0.009) and borderline significance at the 50th percentile, while overall category‐free NRI and IDI were not significant (Table S2). 4.
The authors claimed that despite its borderline significance, the lower dose did not impair the outcome and provided better eye sparing with fewer side effects [ 53 ].
A negative correlation with borderline significance between the estimated glomerular filtration rate (eGFR) and recovery time from metabolic acidosis was observed in the severe AKI group.
falciparum prevalence was higher using ultra-sensitive detection methods as compared to 18S rRNA qPCR, with borderline significance (McNemar’s Chi 2 , p TARE-2 = 0.068, p var ATS = 0.083).
Additionally, ICN students were more likely to use the optional online nutrition modules and, with borderline significance, to report greater desire for additional time dedicated to nutrition.
Hence, I would like to share some thoughts that may improve the presentation of data? General: I would strongly recommend the authors to not use borderline significance, unless more stringent discussion on how to interpret the data should be made.
In an investigation of the association between traffic noise and colorectal cancer incidence in the Danish cohort, an association with borderline significance was observed between road traffic noise and colorectal cancer, which was mainly restricted to distal colon cancer ( 202 ).
In contrast, there was a trend with borderline significance that showed higher BA.4 and BA.5 escape in people living with HIV who were unvaccinated (Fig.
This study suggests that the factors with borderline significance and low level of evidence need to be analyzed further to achieve genuine associations.
found serum folate levels were significantly and positively correlated with HDL cholesterol and negatively with TAG, although the latter showed borderline significance [ 48 ].
Presentation as STEMI tended to be more prevalent among patients with higher SLOS and PAV (borderline significance for the latter).
VSEAPL showed only borderline significance before correction and did not remain significant after FDR correction.
The impact of lidocaine dosage (mg/kg) on pain relief showed borderline significance, while an increase in ketamine dosage (mg) was still associated with clinically meaningful pain relief.
Although there was a borderline significance, authors of a cohort study conducted in France identified twice the rate of transfers of newborns to intensive neonatal care among women aged 40 years or older 30 .
For two polymorphisms, PER3 rs2640908 and GRIN2B rs7301328, a borderline significance was observed.
In rs2234693, the variant allele (T) showed a borderline significance in MA patients in the primary cohort.
This enabled a probabilistic interpretation of the results, providing additional insight, especially in the presence of substantial heterogeneity and borderline significance in frequentist analysis.
1–3: HR = 2.09, 95% CI = 0.99–4.41; p = 0.035) and PSA levels (HR = 1.00 per unit increase, 95% CI = 1.00–1.001; p = 0.033) demonstrated borderline significance, though their confidence intervals marginally overlapped the null value.
Female sex, high scores on anxiety and depression, the use of benzodiazepines (“borderline significance”) and the use of drugs for insomnia was significant more common in patients with high GSRS-IBS score.
As noted in the introduction above, these analyses were driven by theory, in addition to the initial statistical significance of the time-glioma interaction and borderline significance of the age interaction in the AMORIS data.
Although we found a near-significant correlation between EBV-miR-BHRF1-2-5p and disease-free survival, we cannot confirm this relation due to the borderline significance.