“borderline significance”

Apo(a) showed a borderline significance, indicating a negative association with GA at preconception and pregnancy.

In multivariate logistic analysis, after adjusting for age, gender, smoking history, hypertension, and LDL-cholesterol, YLK-40 levels showed only borderline significance.

Findings with borderline significance should therefore be interpreted with caution and require replication in larger cohorts.

Conjunctival scarring was associated with modestly increased expression (>1.2 FC) and borderline significance of several chemokines and cytokines ( CCL2, CCL20, CXCL5, CSF3, IL1B, IL8, IL10, IL21, IL33, FGF2 ) in the multivariable linear regression models (Table 5 ).

We found that only hsa-miR-652-3p showed dysregulation in AIS patients with severe stroke, but this was with borderline significance (fold change = −1.23, FDR = 0.05).

Atrial fibrillation also increased the risk for the combined endpoint with borderline significance ( Table 4 ).

However, borderline significance allows for speculative discussion only.

Age had a borderline significance of 0.053.

A polymorphism rs13041792 of the GSS gene was also associated with disease risk, but at a borderline significance level.

The effect remained of similar magnitude in weighted median approach (OR (95%CI) = 1.006 (1.002–1.01), P = 0.004), but attenuated to borderline significance in MR-Egger regression (OR (95%CI) = 1.004 (1.00–1.01)).

In the Cox models run as a sensitivity analysis for the consensus classifications for CVD and cancer deaths, the HRs for the FI remained essentially the same (cancer mortality HR 1.06, 95%CI 1.00-1.13, p=0.05; CVD mortality HR 1.12, 95%CI 1.08-1.16), yet the former association was attenuated to borderline significance.

Third, the relatively small sample size may have limited the statistical power of multivariate analyses, particularly for variables with borderline significance (e.g., stenosis distance ≤ 1 cm).

Negative progesterone receptor ( p = 0.058) and lymph node ratio > 0.2 ( p = 0.076) displayed borderline significance.

With regards to BNP in the three groups of FA-UA there was borderline significance.

However, the prostate volume (OR, 0.99; 95% CI, 0.99-1.01, P =0.052) and a duration of intravenous antibiotic administration>72 hr (OR, 1.52; 95% CI, 0.99-2.33, P =0.055) showed borderline significance ( Table 2 ).

26 However, in the present study, it showed borderline significance on multivariate analysis and the effect size of the odds ratio was not small.

The rate of readmission for PPM placement was higher in the surgical ablation cohort (4.2% vs 2.8%; P = .055), but with borderline significance ( Table 4 ).

In contrast, only borderline significance was found for age and mismatch repair status.

However, after controlling for other relevant trial characteristics, these differences reached only borderline significance.

Although the ΔHtSDS were comparable within bi-weekly PEG- rhGH, weekly PEG-rhGH and daily rhGH in sub-study-3, a borderline significance trend was observed after 39-weeks follow-up between the bi-weekly and weekly PEG-rhGH.

After adjustment for rs4268748, expression levels of CDK10 in non-sun-exposed skin and FANCA in LCLs retained borderline significance for association with cSCC, with nominal association P -values of 0.0026 and 0.0025, respectively (Table 2 and Supplementary Table 10 ).

A larger sample group would help to estimate the role of genes with borderline significance in patients with adverse remodeling, such as TGF-β1 , ADAM17 , and FTO.

We acknowledge that most of our associations reach borderline significance and are not corrected for multiple testing.

Second, our sample size was small, and the borderline significance of the association between cavitary disease and time to conversion may reflect a lack of power.

Albeit the passive-constructive capitalization responses in this current Malaysian study yielded borderline significance in positively predicting satisfaction, the preliminary correlation demonstrated that this capitalization response had a weak but non-significant relationship to satisfaction.