20 In our present study, the consumption of soybeans products was also associated with MI, but this association showed only borderline significance.
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“borderline significance”
In the literature
Furthermore, the borderline significance of the nonlinearity test suggests that this finding should be interpreted cautiously and requires validation in larger cohorts with greater statistical power.
Nonetheless, a stronger treatment effect with borderline significance was observed in patients with lung and/or liver disease for alpelisib [ 97 ].
However, the differences between the CRKP-NA and CRKP-PA groups showed borderline significance with an Adonis R 2 value of 0.053 and p value of 0.056.
Hypertension was significantly increased in the smoker ( p < 0.01), ex-smoker ( p < 0.05) and COPD groups (and p < 0.05) compared to controls, while the rate of cardiovascular disease was increased in ex-smokers with COPD with borderline significance and smokers with ILD ( Supplementary Table S2 ).
Third, although we assessed all reported genome-wide significant SNPs documented for pancreatic cancer in GWASs, it is likely that other risk variants with borderline significance were not captured.
Tumor resection is a contributor with borderline significance in multivariate analyses for progression-free and overall survival in the LA-STS subcohort, and ICE + RHT might therefore lead to improved survival for patients with otherwise dismal prognosis due to the impossibility of sufficient tumor resection.
Group 1 remained associated with hemorrhagic transformation with borderline significance, Group 2 did not remain independently associated with any outcomes, and Group 3 remained independently associated with mortality (but the strongest predictor of death was NIHSS score) and, with lower significance, with disability and oxygen administration.
The method of electrode placement (P=0.071) and patient age (P=0.066) showed borderline significance as risk factors for LTPFS ( Table 3 , Figs. 2 , 3 ).
The number of medications used per day and IADL scores (borderline significance) were higher in the RLS group.
Family food insufficiency at 1.5 and/or 4.5 years increased the likelihood that a child followed the late-onset, but not the early-onset trajectory by nearly two-fold, albeit at a borderline significance level.
Nuclear pleomorphism showed borderline significance for association with recurrence of PUC-Ta (Table 3 ).
Differences between Observers 1 and 2 were smaller and less consistent, reaching borderline significance at T1–T2, and were not significant at T3.
Nevertheless, the borderline significance and absence of detailed classification regarding exercise type and intensity necessitate cautious interpretation and warrant further investigation [ 61 , 62 ].
A meta-analysis of biomarker studies based on three cohort and seven case-control studies found a significant protective effect for total ω-3 PUFAs, but only an inverse association with borderline significance for α-linolenic acid in case-control studies.
At C3, only NI remained statistically significant (AUC = 0.637, p = 0.007), while NS (AUC = 0.586, p = 0.089), N (AUC = 0.587, p = 0.086), and TI (AUC = 0.596, p = 0.058) showed borderline significance.
Likewise, Oja et al 15 showed significant positive effects on maximal oxygen consumption and resting heart rate (RHR) compared with a no-exercise control, with borderline significance for fat percentage.
Fewer IVS nights (expressed as <4 nights/week vs ≥4 nights/week) achieved borderline significance as a protective factor (OR, 0.113; 95% CI, 0.012–1.009).
Whereas, on univariate analyses, several characteristics at admission were significantly associated with the primary outcome (higher BMI, male gender and previous treatment with RAAS blockers, the latter two of only borderline significance), on multivariable analyses, only BMI remained positively associated with the primary outcome [odds ratio (OR): 1.28; 95% confidence interval (CI): 1.10–1.47].
PSA at 12 months showed only borderline significance.
A value of p < 0.05 was considered statistically significant while a p -value between 0.05 and 0.10 was considered as of “borderline significance”.
A large study by Ludvigsson confirmed the protective effect of CD, but with borderline significance [ 31 ].
With a borderline significance, the percentage of lymphocytes was increased in the whole group by 1.91% and in the women group by 5.42% ( Table 2 and Table 3 ).
An increased overall risk of leukaemia with borderline significance was observed for paternal ELF-MF exposure at conception (OR=1.11, 95% CI 1.00 to 1.22) (online supplementary figure 1 ) but not for maternal ELF-MF exposure during pregnancy (OR=1.04, 95% CI 0.92 to 1.17) (online supplementary figure 3 ).
Three Uniref gene families were weakly correlated with plasma TMAO with borderline significance (Table 3 ).