Biomarker analysis showed variations in inflammation and oxidative stress by severity, with borderline significance, P = 0.049. serum Selenium levels were highest in HFpEF (98.4 μg/L) and lowest in HFmrEF (59.1), increasing in HFrEF (78.7) and severe HFrEF (89.2).
Another study of intrahepatic CCA with 53 patients found that CD3+ lymphocytes had a borderline significance (P=0.049) for independent positive impact on OS while FOXP3+ lymphocytes presented possible independent negative impact (P=0.044) ( 23 ).
ORR for patients with del(17p) was lower than for those without deletions with borderline significance, using Fisher's exact test (21.7% vs 47.1%, P =0.049; odds ratio: 0.31; 95% confidence interval: 0.10 and 0.93).
For the B cells, most of the datasets showed a significantly decreased, except the IDH wildtype astrocytoma of the CGGA data, which only showed borderline significance ( p = 0.049 ) and weak correlation (r = 0.093).
Although a borderline significance was observed between gender and the desire to work abroad ( p = 0.049), post-hoc pairwise comparisons revealed no significant differences, a finding attributed to the small subgroup of students who preferred not to specify their gender and who demonstrated a high propensity for working abroad.
However, the bivariate analysis showed a borderline significance level ( p = 0.049), which was an argument to include sex as a covariate in the multivariate analysis.
Nevertheless, relatives of children with primary headaches had a more frequent occurrence of migraines or cardiovascular diseases, such as hypertension, ischemic heart disease, myocardial infarction and stroke with a borderline significance ( p = 0.049).
[ 13 ] showed borderline significance ( p = 0.049) for solitary metastasis in terms of OS, in a series of 321 OM patients treated with SBRT.
In multivariable analysis, SRCs were significantly and independently associated with dissection, although with borderline significance, likely due to a lack of statistical power from limited sample size (adjusted OR: 2.30; P = 0.049).
The KRD regimen showed borderline significance (median PFS: 13.54 vs 23.41 months, p = 0.049), while the trends in both E-IRD (median PFS: 13.41 vs 21.61 months, p = 0.441) and L-IRD (median PFS: 11.57 vs 9.18 months, p = 0.785) groups were insignificant, Fig. 3 .
Although the sensitivity of DBT plus FFDM was lower than that of MRI plus FFDM at the borderline significance level (59.9% vs. 75.3%; p = 0.049), the NPV was not statistically different.
While this was not statistically significant for either patch size versus placebo (41/267 of participants; 15.4%) in the ITT-LOCF population, the 10-cm 2 rivastigmine patch did reach statistical significance versus placebo in the ITT-OC population (p = 0.034) and borderline significance in the MITT population (p = 0.049).
The levels of miR-429 levels showed a borderline significance with gross residual tumour (>1 cm, P =0.049; Supplementary Table S2 ).
Increase with borderline significance of TNFα in GrpP from week 3 to week 7 ( p = 0.049) and reduction of IL-6 in GrpM Lo from week 3 to week 11 ( p = 0.044) were observed.
Logistic regression identified four variables independently associated with 28-day mortality: SOFA score at ICU admission ( P < 0.001), pulmonary site of infection ( P = 0.005), and fungal infection ( P = 0.003) were associated with worse outcome, whereas intravenous chemotherapy within 3 weeks prior to ICU admission was protective at borderline significance ( P = 0.049).
There was a negative correlation between the rise in TOS/TOC after the maximum-intensity exercise and the length of time a participant was considered to be hypoglycemic with glucose levels < 54 mg dL –1 ( p = 0.028; r = −0.40) and < 70 mg dL –1 ( p = 0.034; r = −0.38), as well as a positive correlation, at a borderline significance, between Δ TOS/TOC and the time spent with continuous glucose monitoring result of > 140 mg dL –1 ( p = 0.049; r = 0.36) and median glycemia ( p = 0.05; r = 0.35) ( Table 6 ).
The rates of other comorbid diseases, including diabetes, tumor, heart diseases, and chronic kidney disease, were not different between the 2 groups (all, P > 0.05), and the Charlson Comorbidity Index (CCI) score was higher in patients treated with ACE-I or ARB, with borderline significance (4.1 ± 1.7 vs 3.3 ± 2.4; P = 0.049).
Models of wGRS2 showed borderline significance ( P = 0.049), indicating that this model might not be well-calibrated.
The average expression of these 100 genes was significantly lower in both responders and non-responders compared to healthy controls ( p < 0.05); however between responders and non-responders, responders showed higher expression with borderline significance ( p =0.049, Figure 2D ).
Current smoking is associated with LVEDWS with borderline significance ( P = 0.049).
Similarly, tumor size shrinkage showed borderline significance (HR: 1.00, 95% CI: 1.00–1.01, p = 0.049) ( Fig. 7 b) ( Table 5 ).
17 Although we found in our cohort a borderline significance ( p = 0.049) for a higher Dandel’s index at baseline in patients with SSc-PAH than in those with IPAH (which would suggest a better adaptation), taking into account the multiple comparison analysis performed, we can only conclude that this index was not able to capture the increased risk of patients with SSc-PAH in our cohort.
When we analyzed combined female/male genotype, we observed that AA/AC genotype of the 1298 MTHFR polymorphism was more frequent in RSA and RIF groups than in the control group, but only in the RSA group was borderline significance achieved ( S3 Table , p = 0.049, OR = 1.49), which was lost after the correction for multiple testing ( p corr . = 0.44).
An association with a borderline significance was observed between marital status and IDDS (p = 0.049).
There was borderline significance association between age of the client and client satisfaction (OR = 1.02; 95% CI: 1.00, 1.04, p-value = 0.049).