Borderline significance toward enhanced production or cellular responses to NO was detected in our pathway analysis, which could suggest that NO biology may still be a promising therapeutic target for age‐related HFpEF.
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“borderline significance”
In the literature
The association with chlamydia and/or gonorrhoea diagnosis at baseline achieved borderline significance (aRRR 2.66; 95% CI 0.99–7.11).
Control over decisions about who to associate with outside of the household had borderline significance.
In the overall study population, EFS partially mediated the relationship between obesity and breastfeeding duration (ACME: −9.3; 95% CI: −29.0, −1.0) and showed borderline significance for EBF at 6 mo (ACME: −0.02; 95% CI: −0.05, 0.0).
When comparing CPRs and CLBRs according to subfertile causes, CRPs was significantly different and CLBRs was different with borderline significance.
5B ), with borderline significance in the VDB (Fig. 5C ).
Although there is controversy regarding the relationship between age at menarche and postmenopausal osteoporosis [ 2 , 6 ], it seemed to have borderline significance in our study.
Conclusion In an RCT, liraglutide treatment in women with PCOS reduced levels of the cardiovascular risk biomarkers MR-proANP with 25% and MR-proADM with 6% (borderline significance) compared with placebo.
Results were published after the first phase of the 20-week randomized controlled part of the study, with significant changes reported (albeit with 1-tailed statistical tests) on most primary cognitive outcomes on CGIC, CDR-SB and CDR Global tests, along with borderline significance in the ADAS-Cog test ( Table 2 ).
However, all HMECs showed borderline significance (i.e. ratios close to 1.0) for being identified as claudin-low, thus suggesting that these normal cell-type lines have mixed claudin-low/basal-like characteristics.
However, hardly the revealed changes with a borderline significance level (p = 0.045 / 0.049) are essential from a physiological point of view.
In the present study, we show that a larger preoperative angle of deviation predisposed to lower surgical success rate in intermittent exotropia with borderline significance.
Although PON1 activity did not differ significantly between the three groups (borderline significance), MASLD + T2D patients exhibited significantly lower PON1 activity compared to the CG.
Thirdly, contrarily to our expectations, we did not observe any significant association between different types of diabetes treatment and risk of hospitalization (although there was a borderline significance for the sulfonylurea drug users).
Aneurysms tended to be larger in the eccentric group with a borderline significance.
As a complementary role of PEC-CT to CT, PET-CT tends to show better prediction about resectability than CT with borderline significance, especially due to unexpected distant metastasis.
Furthermore, Radscore between the two response groups had borderline significance with P value of 0.05 in the test set at TP1, suggesting that the radiomics signature might be slightly over-fitted to training set.
Collagen dressing showed borderline significance in superiority of healing over conventional dressing in the subgroup of patients in whom wounds were less than six months in duration.
Indeed, one unit (in log scale) rise in CD14+ expression on extracellular vesicles was associated with a 3.7-fold significant increase in the risk of MACE; and the effect size remained similar (yet higher in magnitude) after adjusting for the confounders (albeit with borderline significance).
Tibial NCV ( p = 0.0625) showed borderline significance for improvement between the 1st and 2nd examinations in group Tx1. 3.4.
TNF-α ( p = 0.066) followed a similar pattern, with a 42.8% elevation and a 1.75 FC change, further supporting its early relevance despite borderline significance.
Caution should be exercised when considering the association between better survival and aspirin use in the PTGS2-high subgroup given the borderline significance and multiple hypotheses tested.
In the present study, however, we found that the foveal slopes were flatter in women than in men, with a significant difference in the temporal slope and borderline significance for the nasal slope.
Low IL-15 expression was associated with poorer EFS with borderline significance but was not significantly associated with OS ( p = 0.05 and 0.41, respectively) compared to high IL-15 expression ( Figure 5 B,E).
A cox regression model excluding septrin identified ECOG performance status as the only factor with borderline significance (Table S3 ).