“borderline significance”

The promoter region containing the unfavorable C allele (rs3814039_C) exhibited a reduced activity compared to that harboring the G allele (rs3814039_G) with borderline significance (P=0.094, Fig. 2 A).

The number of cycles revealed a statistical significance improving OS rate both in POC (HR=0.904, 95% CI=0.836–0.977, P =0.011) and PEC (HR=0.887, 95% CI=0.798–0.986, P =0.026), while only in POC did the TAC show an increasing trend of risk with borderline significance (OS: HR=1.008, 95% CI=0.999–1.018, P =0.094; PFS: HR=1.009, 95% CI=1.000–1.018, P =0.055).

Among patients treated with anthracycline‐based chemotherapy (n = 531), BRCA1 mRNA low expression patients had a significantly higher pCR rate than intermediate or high BRCA1 mRNA expression groups (24.6% vs 16.8% or 14.0%, P = .031) and retained borderline significance (OR = 1.54, 95% CI = 0.93‐2.56, P = .094) in multivariate analysis.

For TNM stages, patients with advanced stages tended to show increased BLR and SLR with borderline significance ( p = 0.094 for BLR and p = 0.080 for SLR).

The only factor with borderline significance was dyslipidemia with medication (P=0.094).

Third, the borderline significance of PRMT5 according to multivariate analysis ( P = 0.094) suggests that although PRMT5 has potential as a prognostic marker, its predictive value still needs to be verified in a larger cohort.

Multivariate analysis identified v e as a significant independent predictor for treatment failure ( P = 0.022), whereas MTV showed a borderline significance ( P = 0.095).

Results While no significant overall association was observed between genotypes and asthma risk [AG versus AA: odds ratio (OR)=1.31, 95% confidence interval (CI)=0.82-2.09, p =0.3117; GG versus AA: OR=2.42, 95%CI=0.69-8.46, p =0.2833], a borderline significance was found for the G allele (OR=1.44, 95%CI=0.96-2.15, p =0.0950).

Analogously, the correlation between 17β-HSD10–cypD and 17β-HSD10–Aβ complexes was not significant in Tg animals (R = − 0.071, p = 0.845), however, the result of Z-test indicated only borderline significance (p = 0.095).

The results showed that patients with episomal form of the virus had a better disease free survival as compared to those with the integrated form of virus, although with a borderline significance ( P =0.095) (Data not shown).

In the patients with left colon cancer, mutations in ERBB3 were not associated with the overall survival (Figure S4C ); while those with right colon cancer and ERBB3 mutations experienced worse overall survival with a borderline significance ( p = 0.095) (Figure S4D ).

The number of BMs showed a borderline significance associated with OS (p = 0.095).

By multivariate analysis, age (HR: 1.06, 95% CI: 1.02–1.10, p = .003) and LVEF < 50% (HR: 4.71, 95% CI: 1.7–12.90, p = .003) remained significantly correlated with long‐term cardiac death; however, successful CTO PCI showed borderline significance (HR: 0.42, 95% CI: 0.15–1.16, p = .095) and LAD IRA become insignificant (Table S3 ). 3.6 Successful versus failed CTO PCI The procedural characteristics and in‐hospital results of CTO PCI are listed in Table S4 .

Among these 41 circulating inflammatory factors, MR‒Egger analysis revealed four inflammatory factors with borderline significance: B_NGF [OR=1.0242, 95% CI: 0.9960–1.0532; P=0.0951]; EOTAXIN [OR=1.0191, 95% CI: 1.0001–1.0385; P= 0.0511] (with significant horizontal pleiotropy, pval=0.0433); HGF [OR=1.0165, 95% CI: 0.9972–1.0361; P=0.0965]; and IL_12_P70 [OR=1.0160, 95% CI: 0.9978–1.0346; P=0.0880].

By Type of Statin Used Stratification by statin type (Figure 14 ) did not yield statistically significant between‐subgroup differences, though the p value approached borderline significance (random‐effects: Chi 2 = 6.36, df = 3, p = 0.0954).

In a post-hoc (Bonferroni) analysis the differences reached statistical significances in the prediabetes vs the NGT group (p = 0.046) while a borderline significance was found between NGT vs DM (p = 0.096).

After adjusting for osmolality, GFR, UACR, use of anti-hypertensive agents and use of statins, the serum adropin level showed borderline significance (adjusted odds ratio (aOR) 1.001, 95% confidence interval (CI) 1.000-1.003, P = 0.096) between subjects with diabetes and controls. 3.3.

The proportion of diabetic patients was higher in the group with an ISR >50% than in the group with an ISR ≤50% at borderline significance ( p = 0.097).

Subjects in the placebo group exhibited significant negative correlations between the 2‐year change in ROA and baseline performance on HVLT‐R DR ( r = −0.21, p ≤ 0.05) and MMSE ( r = −0.2, p ≤ 0.05), with category fluency reaching borderline significance ( p = 0.097).

It is worth noting that there was a tendency (with borderline significance) to higher prevalence of cardiogenic shock in the non-survivor group (50% vs. 15%, p = 0.097).

The rate of permanent pacemaker insertion approached borderline significance in favor of MS (OR: 0.54, 95% CI: 0.26‐1.12; P = 0.097) 18 .

NACT showed borderline significance in its association with pain severity on POD 7 (χ2 = 6.320, p = 0.0970), suggesting that it might influence pain levels, although this association did not reach statistical significance at the 0.05 level.

CRP levels decreased more in the fenofibrate group than in the comparison group in patients with a BMI ≤26 kg/m 2 with borderline significance (-1.21±1.82 mg/L vs. -0.89±1.92 mg/L, p=0.097).

A borderline significance (p=0.097) was observed, also in 2D panoramic views of the test group, for the same distance comparing premolars (4.1 mm) and molars (6.8 mm).

However, for male mice only, P value reach borderline significance P = 0.097 with significant difference in tumor size for days 11 and 13 ( P = 0.047 and 0.019, respectively) Fig. 7 .