Barely Significant
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“borderline significance”

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borderline significanceP = 0.071.4× alpha
Six DEGs (PARP1, DUSP23, PCDH17, PSEN2, H3f3aos, EPHX1 ) located to the QTLs Perio 3 and Perio4 ( Table 1 , H3f3oas and Dusp 23 have no human orthologous and showed only borderline significance with P = 0.07). 15 DEGs had been reported in previous human GWAS on periodontitis with P < 9 × 10 −6 ( C1orf 87, HLA-DOA, BIRC 5 , CCDC 13 , GLDC, GPR 141 , OTOF, IFI 16 , ETNK 2 , TTLL 11 , ATP 5 S, GRID 1 , LBP, NIN , and VAV 1; Appendix Table 4 ) .
borderline significanceP = .0701.4× alpha
Significant better results ( P < .05) were detected in the open-skilled physical activity group when compared with the no physical activity group in the Benton Judgement of Line Orientation, Stroop (CW), Stroop (W), SRL-SRS (Evaluation) and borderline significance ( P = .070) was found for Trail Making B.
borderline significancep =0.071.4× alpha
In multivariable modeling of the association of these risk factors (including cervical dilation with borderline significance) with cesarean birth in this subgroup, labor duration of longer than 24 hours (RR 3.6, p =0.07) and likelihood of cesarean birth with each increasing centimeter of cervical dilation on admission (RR 0.8, p =0.07) had borderline significance.
borderline significancep=0.071.4× alpha
Though, when focusing on the potential factors associated with progression and survival ( Table 4 ), the Cox proportional hazards regression analysis showed lymphadenectomy not significantly influencing DFS (hazard ratio [HR]=0.59; 95% CI=0.32–1.08; univariate analysis p=0.09), while a borderline significance was shown for DSS (HR=0.14; 95% CI=0.02–1.21; multivariable analysis p=0.07).