Dynamic HALP Score as a Time-Dependent Prognostic Biomarker in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation.

Cancers (Basel) · 2026 · PMC13204590 · PMID 42192929

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0830

boldest claim

The sentences

borderline significancep = 0.070so close (0.05 < p ≤ 0.1)

In contrast, HALP at day +100 maintained and strengthened its association with PFS after adjustment (HR: 3.27, 95% CI: 1.45–7.38; p = 0.004), as did ΔHALP at borderline significance (HR: 1.97; p = 0.070).

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borderline non-significantp = 0.083so close (0.05 < p ≤ 0.1)

In contrast, for OS, no HALP-based cut-off demonstrated a statistically robust association, with only a borderline non-significant result observed for HALP at diagnosis ( p = 0.083), while the remaining HALP-based cut-offs were not significant ( Table 3 ).

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