Similar patterns were observed for the ER+PR− and ER−PR+ subgroups (Table 3 ; Figure S2A–S2B ), with the > 80 mm tumor groups exhibiting borderline significance (ER+PR−, HR 1.253, 95% CI 1.009–1.555, P = 0.041; ER−PR+, HR 1.590, 95% CI 1.012–2.498, P = 0.044).
Unsurprisingly, Group Novel outperformed Group Familiar, updated D2: t (14) = 4.58, p < .001; cumulative D1: t (14) = 4.53, p < .001, while the difference in overall exploration times for the two groups was at borderline significance, t (14) = 1.88, p = .041 (one-tailed).
The same borderline significance was reached also for data acquired from Actiwatch analysis (Student's t-test; P = 0.041) where the mean number of daytime naps was significantly higher in AD patients (1.76 ± 0.61, n = 4) than in controls (0.17 ± 0.05, n = 4).
Subgroup analysis showed borderline significance in the 0–6 year age group ( P = 0.041, Benjamini–Hochberg adjusted P = 0.147) (Fig. 4 b).
When comparing stimulation therapy and donepezil head to head, time-trend analysis showed non-significant changes for CDT and ADAS-Cog, whereas the MMSE test showed borderline significance (p = 0.042) (Table 5 ).
However, this difference between the categorized Katz ADL and DDS showed a statistically borderline significance ( p = 0.042).
However, the results changed to borderline significance after adjusting for clinical covariates in the analysis (p = 0.042), and the genotype at rs27072 did not modulate the methylation levels.
The borderline significance favoring the FAI over mean attenuation ( p = 0.042) should be interpreted with caution given the multiple comparisons performed.
TCGA dataset analysis of stage I, II and III NSCLC revealed no statistically significant difference in survival between high and low MSI2 mRNA levels among these stages ( Figure 3B ), with borderline significance (P=0.042) at stage III.
Calves raised in the pastoral system were predicted to have approximately double the odds of having diarrhea compared to mixed crop–livestock calves, but this finding had borderline significance ( p = 0.042).
Regarding HRCT parenchymal-interstitial abnormalities, linear and/or irregular opacities were present in 31.6% of the patients in the CVID group and in none of those in the CVID-like group, with borderline significance ( P = 0.0427, Table 2 ).
Notably, both 4-MP and ALDA-1 suppressed fluorescent protein spreading by borderline significance in non-treated VL-17A cells ( p = 0.043 and p = 0.05), suggesting that the basal level enzyme activity of ADH and CYP2E1 (Figure S1 ) and the pathway targeted by the drugs has some stimulatory effect on mitochondrial dynamics.
Interestingly, only CRAE reported a borderline significance where the mild NPDR group had 1.05 times the risk of having wider CRAE (OR: 1.052, 95% CI: 1.002–1.105, P = 0.043).
The analyses reached only borderline significance and being lower in patients with DAI (tau p = 0.043 and S100B p = 0.059), presumably because the non-DAI patients still had had more mixed-density lesions with greater parenchymal volume affected, though smaller than 25 cm 3 .
Higher hs-cTnT (ln) was also associated with the triggering condition at borderline significance when forcing this as additional variable into the model (β = 0.061; p = 0.043).
The mean (±SD) age for normal screening was 44.6 (±10.9) years versus 41.3 (±10.5) years for abnormal screening with borderline significance ( p = 0.043).
There is only one previous study by Odueyungbo et al .[ 29 ] (257 HIV patients), that has validated this correlation in HIV patients with borderline significance ( r = −0.126, P = 0.043).
In a cohort of 1946 breast cancer cases, they observed six carriers of the missense variant c.468T > G (p.I156M) (0.3%), which was not identified in any of the 1408 controls tested, giving a borderline significance ( p = 0.043).
The risk alleles did not correlate with myelosuppression, and the strongest borderline significance (not withstanding adjustment for multiple testing) was for rs1901440 (neutropenia, p = 0.043) and rs11719165 (leukopenia, p = 0.049) where the risk alleles trended towards lower toxicity, contrasting with previous study findings.
Surprisingly, higher T-stage lowered the risk, although with a borderline significance ( p = 0.043).
In the presence of multiple driver mutations, higher numbers of CD8 + sTILs were detected in the tumor center, albeit only with borderline significance ( p = 0.043).
However, despite the borderline significance, our results suggest an atheroprotective role of small LDL (beta = 0.339, p = 0.043).
5 ) stratified by the three groups, T2DM was no significant predictor for MACE in Group I and Group II univariately (Group I: HR = 1.39 [0.59–3.25], p = 0.451; Group II: HR = 1.34 [0.84–2.13], p = 0.214), and there was a borderline significance in patients Group III (HR = 1.46 [1.01–2.11], p = 0.043, respectively).
We also found a weak inverse relationship between carotid IMT and brachial FMD with borderline significance (r = -0.126, p = 0.043).
Results are listed in tables 3 and 4 ; similarly to our Filipino trio association results only rs494723 showed borderline significance (p = 0.0437).