In supplementary analyses where we excluded participants with a history of diabetes, the results remained broadly similar, with similar HRs but mild NPDR becoming borderline non-significant due to loss of statistical power.
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“borderline non-significant”
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This limited precision also applies to borderline non-significant findings, including the unadjusted rest-pain AUC comparison, for which a type II error cannot be excluded.
placebo, the between-group differences for all-cause mortality and CV mortality were borderline non-significant (i.e. upper bounds of the 95% CI just over unity).
However, heterogeneity was significant in the meta-analysis for two variants, and borderline non-significant for a third.
However, this difference became borderline non-significant when men were stratified according to the presence or absence of benign prostatic hyperplasia (BPH).
By contrast, no significant excess risks were found for circulatory, haematologic/immune, or genitourinary disorders, and malignant neoplasms showed only a borderline non-significant increase.
Seven significant risk factors and one borderline non-significant factor could be associated with condemnation rate: drinking system, daily growth, feed withdrawal time, ventilation system, average house size, the presence of recirculation vents, problems with septicemia after the first seven days and the type of feed that was used during the grower phase.
Risk factors for the development of PTLDS In a univariate analysis including all LB patients, the risk of PTLDS was higher for the disseminated/late LB group compared to the EM group with a RR of 3.53 (95% CI 0.98–12.68, p = 0.053), borderline non-significant.
The protein ubiquitination pathway showed borderline non-significant enrichment for the CF phenotype, and the antigen presentation pathway, although showing some enrichment for the down-regulated end of our data set, was also not significant.
Additionally, the association was borderline non-significant and the effect sizes were not dramatically altered from the main analysis, suggesting a loss of power may be responsible for these results.
The borderline non-significant results in the non-HFrEF patients were mainly driven by cardiovascular death as in the subgroup analysis; dapagliflozin decreased HF hospitalisation both in patients with HFrEF (HR 0.64; 95% CI [0.43–0.95]) and without HFrEF (HR 0.76; 95% CI [0.62–0.92]).
Presence of diabetes mellitus at last follow-up was determined by higher fasting glucose at diagnosis (OR 1.017, 95% CI 1.003–1.032); a negative association with UFC was borderline non-significant (OR 0.998, 95% CI 0.995–1.000).
Compared with enalapril, sacubitril/valsartan users were associated with a lower risk of primary composite outcome [hazard ratio (HR) 0.58; 95% confidence interval (CI), 0.45–0.75], heart failure-related hospitalization (HR 0.59; 95% CI, 0.45–0.77), all-cause mortality (HR 0.51; 95% CI, 0.36–0.74) and borderline non-significant reductions in all-cause hospitalization (HR 0.85; 95% CI, 0.70–1.04) and cardiovascular mortality (HR 0.63; 95% CI, 0.39–1.02).
Notably, we found borderline non-significant group differences in child motor outcomes at age 2 years ( Table 4 ).
However, after adjusting for demographics variables, sedentary bouts lasting 1–4 min (β =−0.7; 95 % CI:−1.5, 0.0) became borderline non-significant, while nighttime sleep (β = 0.2, 95 % CI: 0.1, 0.4) remained significant.
In addition, there was a borderline non-significant trend where survival of mosquitoes infected with the HD line was lower than for the RD line ( Table 2 ; Fig. 3 ).
falciparum , where introduction of the L263E mutation through transgenics resulted in borderline non-significant changes in the 50% inhibitory concentrations (IC50s) for artemisinin and its derivatives 21 .
Stroke (sarcopenia-only group): Originally borderline non-significant (OR 1.60, 95% CI 1.00–2.56), now statistically significant (OR 1.66, 95% CI 1.04–2.63).
0.281; U = 10, p = 0.057), a borderline non-significant result that should be interpreted with caution given the very small flightless sample (n = 3).
Only two studies reported change in SER which showed a borderline non-significant result.
Despite considerable visual differences in the survival curves, only borderline non-significant differences were found, which may reflect a lack of sample power.
These findings remained significant in women, but turned borderline non-significant in men when fully adjusted, illustrating a 76% (95% CI 25–148%) increased PR for low HDL cholesterol.
study both found an association between female gender and common mental health disorders (Jones, Rona, Hooper, & Wessely, 2006 ; Mulligan et al., 2010 ) though this was not found in OHMNE Afghanistan studies and was borderline non-significant in the main survey (Jones, in press-a , in press-b; Rona, Fear, Hull, & Wessely, 2006 ).
A shift to 35 gram more milk-based dessert was associated with a borderline non-significant 4% (95% CI, 0% to 9%) lower risk.
Stroke (sarcopenia-only group): Originally borderline non-significant (OR 1.60, 95% CI 1.00–2.56), now statistically significant (OR 1.66, 95% CI 1.04–2.63).