“approaching significance”

Sociodemographic variables that were found statistically significant (or approaching significance level) in bivariate analysis were entered as predictors in the multivariable regression model.

The association between donor age and mortality risk was approaching significance for ages 45 and above and in the 25–45 age range.

other which was approaching significance with a p-value of 0.051.

In addition to these significant findings, several other items (e.g., Questions 6 and 16) demonstrated p -values approaching significance, suggesting further possible behavioral trends warranting further study.

Our observations that statin use associated with a compositionally differing gut microbiota and was approaching significance in its association with higher alpha-diversity, are in line with previous findings, although it is important to note that that our results for beta-diversity might have been influenced by heterogenous dispersion of sample variances between statin users and nonusers. 1 , 20 , 48 , 49 Higher richness and diversity of the gut microbiota has been associated inversely with BMI and triglyceride levels as well as positively with HDL-cholesterol in a cohort of 893 individuals. 50 However, on the species level our study gives mixed results between beneficial and detrimental taxa.

However, when these variables were considered together in a multivariable logistic regression, only five remained in the final model with three associations found to be significant while the other two were approaching significance.

A higher discontinuation rate was observed in patients with HT, with symptoms approaching significance (10.3% vs 0%; FDR-adj.

Post hoc Tukey-corrected contrasts showed that the only comparison approaching significance was Nasal–Frontal vs.

Although approaching significance the test did not reach it suggesting the CASIAN is not statistically significantly better than making this decision based on pure chance.

Two Faecalibacterium ASVs were approaching significance (ASV1) and significantly (ASV2) associated with higher rMED scores (ASV1: rho = 0.3273, p = 0.0514; ASV2: rho = 0.4322, p < 0.01, Figure 3 E).

Other sentinel CpG sites were also approaching significance for interaction after adjustment for multiple testing (see Additional file 2 ) and in all cases Europeans showed larger effect sizes when comparing never and current smokers (See Table 3 ).

Replicating our previous findings with suggestive evidence, we observed that reduced FKBP5 expression was associated with response with approaching significance, and this trend was moderated by the FKBP5 genotype (rs1360780).

NCI-CCCs are more likely to be performing UTS for EC than COMPs or CCPs, although this difference was approaching significance.

Although there were no differences found in the subdomains, the most considerable change with approaching significance was found in the subdomain of occupational life and suggested modifications to be made in the program to emphasize this area.

A p -value of <0.05 was considered significant while p -values of <0.1 were considered approaching significance. 3.

While there were no significant differences between groups in parental education, some might view this finding as approaching significance.

Therefore, we used a p -value of 0.06 to identify the ASV that was approaching significance and compare this dataset to the OTU dataset.

The trend was gradually approaching significance, where the overall results suggest that CKD mice lack a clear circadian rhythm.

Confidence intervals are plotted and are approaching significance for the FAL versus sham comparison.

Considering objective a and regarding the burnout dimensions—assessed using the MBI—a difference approaching significance is noted only in the average scores of the dimension related to work accomplishment, which is found to tend to be significantly higher among those participating in MTAs compared to those who do not participate.

Third, the MHO group exhibited plaque stability similar to MHNW, whereas MANW had a greater plaque burden than MHO and higher IPH prevalence (approaching significance) than MHNW, indicating that metabolic status rather than BMI alone corresponds to atherosclerotic biomarker profiles.

The model for SHAPS was significant (F(6, 38)=7.56, P <0.001, r 2 =0.544): group (patients scored higher: t (44)=4.96, P <0.001) and habenula volume (negative: t (44)=2.79, P =0.008) were significant predictors of anhedonia (higher anhedonia corresponding to smaller volume; Figure 2c ), with no other predictors approaching significance (all P s>0.4).

Number of times ever in love was not associated with any of the outcome variables (although it was approaching significance for commitment).

We did not observe any significant differences in cognitive performance following intervention between equol producers and non-producers, although, within the high-dose group, improvements in spatial working memory in producers versus non-producers were approaching significance.

Statistical significance is reported at level α = 0.05; associations in the multivariate models with p -values less than α = 0.1 are noted as approaching significance to avoid overlooking associations that were not significant because of limited sample size.