The ROI analysis further revealed two clusters in the right pSTS ROI that correlated positively with age reaching significance at the voxel‐level ( P ≤ 0.041) and approaching significance when correcting for multiple comparisons at the cluster‐level ( P ≤ 0.055, Table 3 ).
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Differences for CD4:CD8 were approaching significance ( F (1, 164) = 3.742, p = 0.055).
4 Similarly, five patients in the case group in this study died (all 18 years or older), versus none in the control group, with the difference approaching significance ( P = 0.055).
Log rank analysis showed a difference approaching significance with higher rates of adverse events in patients with cardiovascular disease (p = 0.055).
However, the MCSS (fx) - MCS (nl) partial versus intact group was approaching significance (p = 0.055).
However, there was a statistically significant trend toward greater myopia in the USH2A group (−3.0 ± 2.39 DS) when compared with MYO7A (0.16 ± 2.44; P < 0.001), and ADGRV1 (−0.66 ± 1.13; P < 0.001) and approaching significance for CDH23 (−0.91 ± 2.14; P = 0.055).
Expression of Mrc1 was variable, but elevated following M1 (LPS/IFN-γ) MP treatment approaching significance as p = 0.055 relative to saline treatment.
In addition, the hypomethylation of FKBP5 -12 CpG 1 was approaching significance after adjustment for social-environmental factors (a OR = 0.77; P = 0.055), which indicated that no independent association was detected between hypomethylation of FKBP5 CpG sites and persistent depressive symptoms.
Fluorescein staining scores showed a reduction approaching statistical significance (SMD = −0.68; P = .051), while symptom scores measured by ocular surface disease index trended toward improvement, also approaching significance (SMD = −1.17; P = .055).
We conducted a two way (time × 3, putt distance × 4) ANOVA on this data which showed the main effect of time to be approaching significance [ F (2,10) = 3.94, p = 0.055, r = 0.53] but the interaction effect was non-significant [ F (6,30) = 1.14, p = 0.36, r = 0.19].
Although cetuximab alone or in combination with gemcitabine had no effect on plasma thymidine concentrations, a small decrease in plasma thymidine concentrations (approaching significance, with P = 0.055) was observed after 24 h of gemcitabine treatment ( n = 3–8), a finding that is similar to those of Schelhaas et al.
Univariate measures for IL-4 ( p = 0.001) and IL-7 ( p = 0.033) reported significant main time effects with IL-13 levels approaching significance across time ( p = 0.055), peaking 60-min post-lift.
Reaction time and deoxyhemoglobin The first LV relating reaction time and deoxyhemoglobin concentration was approaching significance ( p = 0.055) and explained 44.3% of the crossblock variance.
Additionally, a comparison of the ERP to objects across hemispheres revealed that the extended Nc to the own name condition on the left was higher in amplitude than the extended Nc to both conditions on the right (P<.002 and P<.003 respectively; interaction of Name by Hemisphere approaching significance F (1,28) = 4.00, P = .055, η p 2 = .125).
An ANCOVA on complete cases for the 12-month weight change adjusted for baseline weight, gender and age showed an effect approaching significance p=0.056 reflecting a difference between the C-IW group of −2.2 kg (95% CI −4.6 to 0.1 kg, p=0.068) compared with differences between the C-I groups −1.9 kg (95% CI −4.5 to 0.7 kg, p=0.228) and the I and IW groups −0.3 kg (95% CI −2.8 to 2.2 kg, p=1.00).
Previous experience in dealing with problems similar to those described in the vignette was also associated with better recognition, and although this finding was not significant, it was approaching significance (P=0.056).
failed to reach significancep > 0.017
Trial times A main effect of model approaching significance [ F (3,33) = 2.783, p = 0.056, ES = 0.202] suggested that trial time was affected by the model being constructed, follow-up comparisons however, failed to reach significance ( p > 0.017).
FANCD2 showed the strongest trend, with variants more frequent among non-responders and a p-value approaching significance (p = 0.056), suggesting a potential link between DDR-related defects and diminished clinical improvement.
In the occipital white matter, ACE‐2 protein level was unaltered across the dementia groups compared to age‐matched controls (Table 2 , Figure 4E ) but was raised in relation to SVD severity ( p = 0.0087) with post‐hoc analysis showing higher levels in severe SVD approaching significance (0 vs. 3; p = 0.056) (Figure 4F ).
However, when this was further explored through treatment x sex analysis, a significant difference was only present between the number of cells in FCMU and FSPG (post-hoc for females; F (1,18) = 23.815, p < 0.001), whereas males were approaching significance (post-hoc for males; F (1,18) = 4.163, p = 0.056).
The main effects of Race and Gender failed to reach the required level of significance, although the main effect of Gender was approaching significance (p = 0.056).
Further analysis of the cognitive data (Faux et al., 2010 ) revealed that, based upon a ranking analysis, the high dose treatment group had a significantly higher proportion of patients showing improvement on the NTB composite z-score and executive factor z -score as compared to the placebo group, with the ADAS-cog data also approaching significance ( p = 0.056).
Following multivariable analysis, gender was approaching significance ( p = 0.056), but only prior medical knowledge ( p < 0.001) remained significant independent of gender, age, first language and employment status (Table 5 ).
Early compared to late intervention had a difference in slope approaching significance for Communication (0.14, p =0.056) and the combined non-motor score (0.33, p =0.052).
The comparison between the baseline and VOC‐positive biomarker values (see Methods ) indicates that the increase, accounting for repeated measurements, was statistically significant for FA‐WB‐Psel ( P = 0·015 ) and was approaching significance for FA‐WBC‐Psel ( P = 0·056).