Barely Significant
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“approached significance”

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In the literature

approached significancep = 0.0531.1× alpha
However, given our a priori hypothesis of reduced eNOS expression in IUGR females—consistent with findings in age-matched IUGR males from the same litter [ 36 ], a one-sided test revealed a trend toward lower eNOS expression in IUGR-ECFCs that approached significance ( p = 0.053).
approached significanceP = 0.0531.1× alpha
4 D ) did not differ between treatments ( P = 0.123) and effects of litter size approached significance ( P = 0.053); transpulmonary pressure increased more in twin‐pregnant than non‐pregnant ewes ( P = 0.020) and the change in transpulmonary pressure did not differ between singleton‐pregnant ewes and other litter sizes (each P > 0.2).
approached significanceP = 0.0531.1× alpha
OnabotA 30 U approached significance compared to placebo on MADRS (mixed-effect model repeated measures least-squares mean difference: −3.7; P = 0.053) and reached significance [least-squares mean differences: −3.6 to −4.2; P < 0.05 (two-sided)] at weeks 3 and 9.
approached significancep = 0.0531.1× alpha
Although the overall interaction of group by time was not significant for Trails B, the comparison of the active treatment group to control approached significance [ t (67.2) = 2.37, p = 0.053; d = 0.85], a difference that became significant at second follow-up [ t (67.2) = 3.03, p = 0.01; d = 1.09].