“approached significance”

Although few significant associations were observed, genes approached significance on chromosomes 3 and 6 in all tissues.

This was the only parameter that approached significance in accounting for the variability observed ( Fig. 1B ).

To first test gene–gene relatedness within cluster 11, we performed WGCNA on the relative, pseudo-bulked expression of the top 5000 most variable genes within this cluster, identifying a total of 20 modules, 7 of which exhibited correlations with sample covariates that approached significance (FDR < 0.1), Fig. 4 b.

In addition, the Prime by Verb interaction was significant in OA and YA, and approached significance in PWA.

There was no difference between the two groups for change in ASES ( p = 0.096; CI: −3.7 to 41.6) and CM score ( p = 0.086; CI: −3.5 to 46.3) though these approached significance.

However, the comparison between middle-aged and older adults approached significance at p s = .027.

However, group phenotype (LRT: χ 2 1 = 8.62, p adjusted = 0.017) was a significant positive factor in the proportion of time spent feeding on fruit, and the effect of individual phenotype (LRT: χ 2 1 = 5.27, p adjusted = 0.054) approached significance after adjusting for multiple comparisons ( n = 242 focal months, Table 1 ).

Two of three processing speed measures approached significance for lower treatment group performance compared to controls.

Though we had made no predictions about female physical formidability and conversational dominance, we carried out the same regressions for females, again finding no results that approached significance.

None of the analyses of off-target transgene expression versus maternal behavior approached significance (Extended Data Fig. 6-2 ).

Education level approached significance but ultimately did not reach the threshold for statistical significance (P = 0.096).

(The difference between groups on “increased depression severity” approached significance; as might be expected given the results of the clinical trial [9] the control group had more recorded instances of this adverse event).

Even these underperforming attributes approached significance, indicating potential relevance with larger or more diverse sample sets.

Having the highest testosterone concentrations (Q4) compared with Q1 approached significance for an association with a decline in executive function and verbal fluency (Q4 vs.

Perhaps, in a larger sample, the blended training would have shown an effect on reducing irritability, as the regression coefficient approached significance and there seemed to be some reduction in irritability over time.

Surprisingly, carotid IMT did not change significantly within supplementation-dose arm, but decreased significantly in the bulb region and approached significance in the CCA within the standard-dose arm.

In the previous N -of-1 factorial RCT of BCTs (Sniehotta et al., 2012 ), across the 10 participants overall, goal-setting approached significance and self-monitoring led to a significant increase in walking.

Although some comparisons approached significance prior to adjustment, the conservative Bonferroni correction reduced statistical significance.

Older patients had slightly lower SVR rates and this difference approached significance.

Post-hoc testing of categorical predictors that approached significance were investigated using the “lsmeans” [ 33 ] and “pbkrtest” [ 34 ] packages in RStudio, for continuous predictors, model estimates were evaluated to determine the direction of any effect.

For the primary endpoint, tafamidis and vutrisiran demonstrated a significant survival benefit over placebo; acoramidis approached significance.

Pairwise comparison showed that PR had longer injury to onboard intervals than FR, but this only approached significance on post hoc testing (ρ = 0.061).

Among different models explored, only the InceptionResNet + LSTM model with clinical feature fusion could stratify the patients into two cohorts with a statistically significant difference in progression‐free survival, with the cohorts identified by the InceptionResNet + LSTM model without any clinical features approached significance.

Changes in subjectively reported moderate-to-vigorous physical activity approached significance over time, but, again, significant interaction effects were not found.

As for covariates, only years of schooling modulated the performance in the Go-No Go test: the effect was significant in the analysis on false alarms ( F (1,179) = 9.86, p < .01) and approached significance in the analysis on RT data ( F (1,236) = 3.66, s ).