Barely Significant
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“approached significance”

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approached significancep = .0661.3× alpha
The difference in effect between clinical and community settings approached significance ( z = 1.84, p = .066), although the other pairwise comparisons were non-significant (clinical v education settings, z = 0.68, p = .498; community v education settings, z = 0.52, p = .604).
approached significancep = .0661.3× alpha
The interaction between target location and relatedness approached significance, F (1, 60) = 3.50, p = .066, η p 2 = .06, and revealed a significant priming effect for top located targets (related: M = 691, SE = 12.73; vs. unrelated: M = 702, SE = 12.53, p = .051) and no priming for bottom located targets (related: M = 728, SE = 12.32; vs. unrelated: M = 722, SE = 11.89, p = .399).
approached significancep = 0.0661.3× alpha
However, estimated differences for CPI Group participants’ MoCA-Blind test scores compared to the ADRC cognitively intact controls approached significance at baseline ( p = 0.066) and were significantly worse than the controls’ scores after CPI treatment (6 months for CPI Group participants’ scores compared to controls’ scores at 12 months, p = 0.011).
approached significancep = 0.0661.3× alpha
To confirm that 4-HNE can activate p53 in adipocytes, we found that incubation of 3T3-L1 adipocytes for 6-hours with 4-HNE increased Cdkn1a mRNA levels 2.9-fold (p = 0.003) and Igfbp3 mRNA expression approached significance (p = 0.066), consistent with downstream p53 activation [ Figure 6 F].