“an overall trend”

Interestingly, an overall trend toward upregulation was observed for DLK1, SPTB/COL21A1, and SAR1A across CHMs, PHMs, and NCs, respectively ( Fig. 6 , A and B ).

The sensitivity correlation computed in normal breast samples (Figure 2 A, left) unveils an overall trend of miRNA-independent interactions between cognate genes ( S ∼0, red background in the heat-map) with the notable exception of a limited pool of miRNAs ( S ≠0, light vertical stripes in the heat-map).

Furthermore, by decomposing the temperature curve into an overall trend (Cope’s rule), the fluctuations around that trend (Bergmann’s rule), and a combination of both (Cope–Bergmann rule) ( 8 ), we found strong support for the latter.

The AWCD is an indicator of total activity and can give an overall trend of metabolic activity of the microbial communities in time ( Tanase et al., 2017 ).

It showed an overall trend of increase, increasing from 0.140 in 1990 to 0.177 in 2015 ( Figure 3 ), indicating that the government and society are gradually increasing their awareness of ecosystem change and environmental quality.

An overall trend is that Gram-negative genera were more abundant in PLA2G2A TGN mice and Gram-positive genera were more abundant in WT mice, consistent with the view that sPLA 2 -IIA preferentially kills Gram-positive bacteria.

2c , there is an overall trend of increased concentration of cytokine secretion in dense matrices compared to loose matrices in statically cultured conditions, with a significant increase in the levels of CXCL8 and TNFα.

The levels of biomarkers of oxidative damage (ROS, PC, and MDA) and mRNA levels of multiple antioxidative enzymes in the head kidney and spleen exhibited an overall trend similar to that of the intestine and skin.

This result is consistent with an overall trend to adaptation and the observed positive value of d ± .

Figure 1e shows an overall trend of inhibition of the three virulence factors in planktonic bacteria culture affected by est816 of 6,12 and 24 U ml −1 .

Interpersonal analysis of trends We could not find an overall trend toward more descriptions of SD experiences when MM manifestation was increased.

The highest annual incidence was observed in 2016 with 813,149 (19.1%) presentations per year, and incidences showed an overall trend of decrease over the years (Table 1).

A recent systematic review [18] of prospective studies with at least 10 adults, ≥ 18 years undergoing bariatric surgery in which PA or physical function was measured pre and postsurgery, found an overall trend for PA to increase up-to 12 months following surgery.

An overall trend for these patients showed an initial increase in aggregate kidney volumes with a peak volume of 410 cm 3 ( Fig 2 ).

An overall trend of decreasing WRS with lower SNRs was observed across lists, consistent with the expected psychometric behavior of speech‐in‐noise performance, although all lists maintained equivalently high scores at each SNR.

HIF-1α was positively expressed in all renal anatomical regions at different time points, exhibiting an overall trend of an initial increase followed by a decrease.

Overall, there was moderate between-country heterogeneity for the effect of temperature on neonatal mortality, with an overall trend towards increased mortality with exposure to high versus moderate temperatures (95th vs 50th percentiles) and decreased mortality with exposure to low versus moderate temperatures (5th vs 50th percentile).

After completion of a sexual health curriculum series, there was an overall trend toward increased knowledge and comfortability with sexual health best practices in the primary care setting of safety net urban health system.

KNI followed an overall trend of decreasing first and then increasing during plant growth ( Figure 7 ). 4.

The measured Zn/Co ratio in the samples differs from that chosen initially, although an overall trend is preserved.

4.2 Treatment protocols No clear single recommendation for radioiodine therapy is available, but there is an overall trend to administer conservative doses. 2015 ATA guidelines were more conservative in dosing approaches than 2009 guidelines [61] , [62] .

Although there was an overall trend toward lower medication adherence for polypharmacy, there was no significant difference in medication adherence between the ODT and non-ODT groups.

Up to a PRR of 10, results stay consistent with minor deviations but an overall trend of the drug interaction network and MGPS outperforming the other methods.

In the same way that a dramatic deviation from an overall trend of a metabolite’s concentration is identified as measurement error via smoothing spline regression, the deviations of many metabolites in one sample can be identified as the result of reference error or a dilution effect.

Figure 2 indicates an overall trend (with variation between years) of increasing numbers of applied joint modelling papers published (although the maximum number published in a year was only 20).