Barely Significant
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“an overall trend”

4,872 sentences · 4,872 papers · 34,210 search hits before verification · confirmed specimen

Sighted at

p=0.2

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Although there was an overall trend of risk decrease, prevalence in several districts presented an increased trend, such as Rasuwa (11.1%, 12.1% and 18.9% in 2006, 2011 and 2016 respectively) in Central Region and Achham (6.9%, 18.2% and 20.5% in 2006, 2011 and 2016 respectively) in the Far-western Region of Nepal.
While AKT1 had no detectable changes to its phosphorylation or abundance, it demonstrated an overall trend towards activation at both timepoints where all but one of its substrates had increased phosphorylation; furthermore, it had a large number of protein-level substrates with altered phosphorylation, suggesting a change to its activity.
Within these differentially expressed genes, an overall trend observed was that homeostatic genes were downregulated while immune response genes were significantly upregulated, such as CXCL9 (Log 2 FC = 13.42, adj. p value = 0.04) and CXCL10 (Log 2 FC = 11.93, adj. p value = 4.43 × 10 −10 ; involved in immune cell recruitment and neuroinflammation); STAT1 (Lo