Barely Significant
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“an overall trend”

4,872 sentences · 4,872 papers · 34,210 search hits before verification · confirmed specimen

Sighted at

p=0.2

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Introduction Despite an overall trend of reduced alcohol use and increased rates of abstinence among young people in Australia and globally, alcohol use remains one of the leading causes of burden of disease globally among people aged 10–24 years ( AIHW, 2020 ; McCabe et al., 2021 ).
TBI induces both morphological and functional changes in MLVs, including increased expression of lymphatic vessel endothelial hyaluronan receptor 1 (Lyve-1), a significant increase in the number of endothelial loops and buds within the lymphatic system, and an overall trend toward increased lymphatic vessel diameter (Bolte et al. 2020 ).
13 , 15 Similarly in our work, there was an overall trend of reclassification from a higher risk category to a lower risk category, which would affect statin eligibility in 19% of this population who were previously statin-eligible according the most recent ACC/AHA primary prevention guidelines using PCE risk stratification. 16 Our analysis suggests that reclassification was generally appropriate with only 83 (3.2%) people who were reclassified from a higher risk to lower risk category went on to have an ASCVD event.
Although there is some discordance between studies, and heterogeneity with regards to cut-offs, adherence and duration of particular diets, disease types and clinical outcomes, there is an overall trend towards better outcomes associated with what is regarded as an healthy diet in humans in general by the WHO ( 110 ).