“an overall trend”

There was an overall trend for a greater number of dense granules and partly filled vacuoles in Anx-A1 null cells, although this was not statistically significant.

In an overall trend, it can also be seen that the highest number of drugs given was cetirizine in Case 1, followed by prednisolone and steroids in Case 3.

The cerebellum of female mice showed less biantennary glycans, an increase in sialylation, and an overall trend toward more complex structures compared to the males.

Cochran-Armitage trend test was performed to determine whether an overall trend was observed in the proportion over time.

There was an overall trend toward decreasing cortical carbonate substitution over time in both groups (Table 3 ).

Owing to an overall trend toward an increased use of cemented THAs in recent years, there was a significantly higher proportion of cemented THAs in the CEF+DOX group (853/3,487 [24.4%]) compared with the CEF group (725/4,430 [16.4%]; p < 0.001).

Taken together, except for the β 2 G254V mutation, which did not affect single-channel openings in all the remaining mutants, an overall trend to shorten the open times was observed, suggesting an increased closing rate compared to that of the WT receptors.

However, an overall trend can still be appreciated.

Thus, although we see an overall trend, the results should be interpreted with caution.

Finally, the 4 th quartile of paternal urinary concentrations of high molecular weight metabolite mCHP was associated with a 7.0 day (95 % CI = 2.2, 11.9) increase in gestational age, compared with the lowest quartile; an overall trend was observed for mean change in gestational age with increasing urinary levels of mCHP (p for trend = 0.005).

Although its role varies across different types of cancer, there is an overall trend suggesting that through targeting specific signaling pathways and genes, miR-128-3p significantly influences the biological behavior of cancer cells ( Fig. 4 ).

Studies have reported an overall trend of increased colonic pH in UC patients, which may drop to 2–3. 44 Finally, various high-concentration digestive enzymes in the gastrointestinal tract have become important obstacles to destroying the structure of curcumin and hindering its effective absorption and utilization.

In addition, Figure 4B shows an absence of an overall trend in the scatter plot of cosine similarity and correlation (h 2 ) values.

We ran survey‐weighted logistic regression first with year only to test for an overall trend, and then with covariates to assess associations with the selected characteristics.

Although visits before November 2011 are presented here to show an overall trend, they were not included in the main analysis since ED diagnoses were not yet recorded for these visits.

Our study also observed an overall trend of increasing CRE colonization in hematological patients throughout the years, aligning with the findings of a multicenter investigation (Fasciana et al., 2023 ).

Furthermore, we observe an overall trend that the fluorescence lifetime and QY of qU agree well between different single-stranded oligomers, as expected.

An overall trend similar to that of D_LMW was observed for formulations in Na-acetate and Na-succinate.

An overall trend for reduction in ischemic heart disease-related mortality has been observed; however, it remains an important disease in the aging society ( GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group, 2020 ; Nowbar et al., 2019 ; GBD 2019 Diseases and Injuries Collaborators, 2020 ).

Results From the analysis of the bacterial pathogens in 485 cases of acute neonatal conjunctivitis patients from 2002 to 2016 in Southern China, there is an overall trend of decreasing detection of Gram-positive bacteria and increasing detection of Gram-negative bacteria from the conjunctival sac secretions.

Similar trends were observed in the spleen, with addition of anti-CD40 treatment leading to significantly decreased percentages of CD4 and CD8 T cells and increased ICOS expression in both subsets compared to debulk only (Figure 5 ).In the tumor, we observed an overall trend towards lower percentages of CD4 T cells and higher activation status in all treatment groups compared to untreated, with the only significant decrease observed in the debulk + IMQ + anti-CD40 group (CD4 T cells, p < 0.05; Figure 7 ).

The negative correlation between height and the Gini coefficients ( r = −0.69, p < 0.01) indicates toward an overall trend of taller stature in times of less income inequality.

There was an overall trend of circulating cytokine increase, indicative of gross peripheral immune activation by chemotherapy, and a significant decline in BDNF levels throughout chemotherapy.

Gender stratification For both men and women there was an overall trend of reduced LBP with time when using baseline as reference.

The overall trend of change in the environmental performance indicator of the Chengdu-Chongqing region from 2011 to 2020, given in Figure 3 , shows that: between 2011 and 2015, the environmental performance indicator of Chengdu City grew at a relatively slow pace, and although there was a decline in 2014, it did not fall below the environmental performance indicator of 2011, and still showed an overall trend of growth.