“an overall trend”

Whereby in APP/PS1 mice with ADAM17 re-expression, we saw an overall trend in the protein profile shifted towards the WT mice ( Figure 8A ).

An overall trend of lower stress-induced PCD levels were observed with proline treatments from 1–5 μM, and significant reductions ( p < 0.05) were noted with 1 μM and 5 μM compared to the BG11 control ( Supplementary Table 4 ).

angustifolia , with an overall trend of substantial suppression.

Results We found that, as the SO 2 concentration increased, the production of total higher alcohols showed an overall trend of first increasing and then decreasing.

Overall, this analysis of the intrinsic variability of the components of the average estimate indicate that the individual words follow an overall trend; Google is reporting document counts that go up and down over time for all words simultaneously.

Pharmacokinetic and immunogenicity analysis Emactuzumab systemic exposure (area under the curve last ) showed a greater than dose-proportional increase from 500 mg to 1000 mg of emactuzumab, accompanied by an overall trend of total clearance decline (range: 346 to 752 mL/day), indicating that the elimination of emactuzumab was predominantly target-mediated following 500 mg and 750 mg q3w dosing in combination with selicrelumab ( online supplemental figure 1 and table 1 ).

We found that according to the RNA velocity trajectory arrows ( Figure 6 B), there seemed to be an overall trend of less differentiated cells having trajectory arrows pointing toward more differentiated cells.

The second dynamic expression pattern, including Clusters 2, 5, 6, 8, 16, 18, 23, 25, 26 and 28, represents genes that underwent an overall trend of decrease, suggesting continued degradation over the pre-implantation period.

Cumulative reporting of individual DEs revealed an overall trend of increased DE reporting as the years progressed ( Figure 2 ).

However, we nonetheless observed an overall trend that was consistent with the results of the analysis of grade II and III gliomas.

The data reflect ups and downs uniform in the last months, so it is difficult to determine an overall trend, unlike the confirmed cases of COVID-19.

Results There was an overall trend of lower Ct values from specimens collected in the early morning, with a gradual decrease of viral load towards night time, but reaching statistical significance only when compared with the specimens collected at bedtime.

Therefore, in this study, top burr width and top burr height have been considered to show an overall trend in the field of micro milling domain.

It is noteworthy, however, that despite the lack of statistical significance in the difference between Epo doses lower than 1000 U/kg compared to sham control, there is an overall trend of increasing physical activity with increasing Epo dose.

However, the median neo-epitope fraction remained identical (0.01) across both quartiles, suggesting that, while there was an overall trend, the effect size might be small.

Pneumonias 10 studies with 5550 participants (3239 on biologics) reported results on pneumonias during the study period, demonstrating that the use of biologics was associated with an overall trend of a 30% reduction of pneumonias compared to the control group (risk ratio 0.70, 95% CI 0.36–1.37, I 2 =0%) ( supplementary figure S22 ).

An overall trend of increased microtubule content was seen, although this was not statistically significant in light of a high variability in microtubule content even in comparing axons of similar sizes within the same animals ( Fig. 4 C).

These aggregates were observed in a subset of hippocampal/subicular pyramidal neurons in the adult, aged, PART, and pAD/AD cases, with an overall trend of increase in their frequency.

Although there were no statistically significant differences between smoking and non-smoking groups, there was an overall trend towards greater GBI means, almost always, for non-smokers ( Figure 4 ).

Furthermore, we could find an overall trend that the spectra of normal nuclei have smaller values than spectra of cancerous nuclei within the wavelength range from 460 to 600 nm and higher values within the range from 600 to 750 nm.

In K562 cells, the smaller fragments, including the 625 bp fragment, showed an overall trend towards stronger expression relative to HeLa cells. 2.1.2.

CCK-8 and wound healing assay results showed an overall trend of cell proliferation over time.

The expression of ZO-1 and occludin demonstrated an overall trend of upregulation after the individual treatment of probiotic V or Met, which was further more significantly upregulated by the two in the combinations.

Spatial correlation analyses indicated an overall trend whereby functional connectivity patterns were more similar between temporally adjacent age groups, with similarity gradually decreasing as developmental distance increased (Figure S7).

A group-wise analysis of these 13 amplicons revealed that hyperT1D–MVPs displayed an overall trend towards greater methylation levels in the affected co-twins compared with hypoT1D–MVPs, although this difference was just short of significance (P = 0.063, Welch's t-test, Figure S3 ).