9 A recent systematic review revealed that since 1999 there has been an overall trend toward medical management for neurologically intact patients with SEA. 8 Medical management typically consists of several weeks of IV antibiotics and close clinical follow-up.
Although an overall trend of increasing homogeneity was observed as the pre-incubation time increased from 0 to 30 min, these results were not statistically significant.
As for apoptosis genes, the expression of P53 ( Figure 4 A) in the treated group showed an overall trend of increasing and then decreasing, and the peak value of the high-concentration group (6 h) was delayed compared with that of the medium and low-concentration groups (3 h); and it was 7.4 times higher than that of the control group.
The median percentage-change in BMI was −2.7%, representing an overall trend of weight loss amongst patients in the cohort, though this ranged from −26% to +22%.
With some exceptions, an overall trend toward time-dependent and dose-dependent activation of Nrf2 antioxidant genes was observed.
This assessment showed an overall trend of worsening STS/TUG with age, although there was a small number of patients in each sub-group.
Discussion of Potential Distribution of G.morsitans under Future Conditions In 2021–2100, the amount of highly suitable area presented an overall trend of increasing first, to a peak, and then decreasing from 2041–2060 under all scenarios—except for SSP126, which would reach its peak in the 2061–2080 period.
Both the sequence diversity and the viral load in this subject fluctuated over time, with an overall trend of increasing viral load and sequence population diversity (Figure 3 a).
In this study, under climate change conditions, compared with the present, the potential habitat areas of GL, LA, NI, and AE on the QTP show an overall trend of expansion in the future, while FD, RT, and AB are generally showed a decreasing trend.
This indicates an overall trend of declining risk of getting infected as a child and adolescent.
This pattern suggests an overall trend toward immune suppression, potentially contributing to a poorer prognosis.
Our analysis is consistent with these reports and more recent studies [47] , [65] , which found an overall trend that pregnant women, mainly in their third trimester, have a higher incidence of hospitalization than the general population.
Although the avian viruses examined in our study were not direct progenitors of the human viruses, the collective data on avian and human HAs within a given subtype show an overall trend to suggest that the acid stability of the HA may play a role in adaptation to humans.
In order to view an overall trend of the so characterized molecules, their concentrations were employed as a basis for an rPCA model, shown in Figure 2 .
We divided into 6-month periods for analysis since September 2019 to February 2020 would represent a pre-COVID-19 pandemic period as well as identifying an overall trend.
From the perspective of the whole iteration process, the distribution of ISGA population individuals has an overall trend from dispersed to concentrated, which effectively helps the algorithm breakthrough the local optimum and improves the convergence accuracy and speed.
Therefore, the pooled estimates should be interpreted as summary indicators reflecting an overall trend rather than precise global parameters.
This finding suggests an overall trend towards citing more contemporary work in recent years.
As an overall trend, weight gain up to 18 months showed consistent positive correlations with body fat percentage and MVPA measured in the first and fifth grades, with some exceptions.
Representative telephone surveys from before and during the pandemic also point to an overall trend toward a decline in mental health measures during the course of the pandemic, particularly in the long term ( 32 ).
There is some variability in the results either side of the borderline (βNTI -2) as scale increases, but upon comparing the results at different scales by regression, there is an overall trend towards determinism at broader scales (Fig. 1 ).
This is consistent with earlier studies that have reported high delta and spindle activity in the hippocampus during NREM 23 , 60 , 61 .When comparing the spectral power between the three subfields, we found that the DG/CA3 showed an overall trend of higher power than the CA1, and SUB, with certain frequency bands showing significant differences (cluster-based permutation test, p < 0.001; DG/CA3 > CA1: 10–11 Hz; DG/CA3 > SUB: 27–30 Hz; Fig. 1b and Supplementary Fig. 2b ).
MCT levels were measured as a marker of mast cell activation, with no significant differences in MCT levels between study groups, with an overall trend for MCT levels to decrease over time in both groups (see Fig E5 in this article's Online Repository at www.jacionline.org ).
Using data from 64 genomes, our results indicate an overall trend for pseudogenes observed in most of the genomes studied.
However, the Japanese government stopped subsidizing high-cost care, such as nursing homes, after the revisions of the LTCI ( 27 ), which promoted an overall trend of shifting from institutional care to domiciliary care.