“an increasing trend”

Compared with the CON group, the Neu5Ac group exhibited significantly higher concentrations of formate and acetate in the jejunum, while acetate levels in the colon showed an increasing trend ( p < 0.05, Figure 6 A,B).

3.4 Effect on the EPO and HIF-1α levels of focal cerebral ischemia reperfusion rat models From the data in Table 5 , compared with the model group, the EPO level in brain tissue of rats in the Nimodipine group and medium and high dosage of chlorogenic acid groups significantly increased ( P < 0.01), and the EPO level in brain tissue of rats in the low dosage of chlorogenic acid group showed an increasing trend ( P > 0.05), and the HIF-1α level in brain tissue of rats in the Nimodipine group and medium and high dosage of chlorogenic acid groups significantly increased ( P < 0.01), and the HIF-1α level in brain tissue of rats in the low dosage of chlorogenic acid group obviously increased ( P < 0.05), sugg

Although an increasing trend of odds ratio is observed with increasing risk score (Additional file 7 ), the OR values are significant ( p < 0.05) only for risk categories 4 and above.

Compared with control piglets, there was an increasing trend of Lactobacillaceae of recipient piglets both on days 12 and 27 ( P > 0.05).

As for IL-1β, it also showed an increasing trend ( P value <0.05) similar to the expression of TNF-α ( Figure 6(b) ).

However, after 30 d, the ADG of the 3 test groups showed an increasing trend, and far surpassed that of the control group ( P < 0.05).

Both LOM LSPV denervation and LSG Denervation significantly reduce cardiac sympathetic nervous activity (lower LF: 1.05±1.14 vs 2.36 ± 2.34 ms 2 in group 2 and 0.51 ± 0.39 vs 2.24 ± 1.53 ms 2 in group 3; and LF/HF ratio: 0.35±0.21 vs 1.65 ± 1.04 in group 2 and 0.27±0.28 vs 1.42 ± 0.77 in group 3; all P<0.05) but neither had a significant effect on parasympathetic nervous activity though which showed an increasing trend (HF: 2.69±2.00 vs 2.01 ± 2.14 in group 2 and 2.66±1.74 vs 1.95 ± 1.60 in group 3, P>0.05).

In addition, the wild-type showed an increasing trend in the immobility time (pre: 50.86 ± 6.18, post: 68.57 ± 6.48, p > 0.05, paired t -test) post CFA injection compared to that prior to CFA injection, whereas Kcnip3 -/- rats showed significantly increased immobility time (pre: 78.14 ± 7.98, post: 108.00 ± 7.06, p < 0.05, paired t -test), suggesting that Kcnip3 -/- rats are more vulnerable to depression than wild-type rats.

In the square–square connected environment, the global fit shows an increasing trend (Figure 2F ) with respect to the LAHN training time (Regression analysis: Global fit R 2 = 0.3826, p < 0.05).

Moreover, an increasing trend of eight TAGs with an even summed carbon number over 56 was observed in VPA-induced ALF (fold change > 1.5, P < 0.05, VIP > 1), and these TAGs showed a pronounced positive relationship with ALT value ( Table 2 and Figure 2D ).

We also observed an increasing trend of ferritin and Fe 2+ levels in the synovium with the progression of K–L grade (Fig. 8 C, * P < 0.05, ** P < 0.01, *** P < 0.001 versus K–L Grade 2; # P < 0.05, ### P < 0.001 versus K–L Grade 3).

Figure 3 A showed an increasing trend in IA ( P > .05) and a significant increase in the Ad‐Suv39h1 group's IA/MA (I/M) ratio ( P < .05) as compared to the Ad‐Null group.

Besides, single lesion gradually developed to multiple ones in the disease progression, with an increasing trend ( P = 0.05) in median affected pulmonary segments (7.0, 9.0, 10.5 and 12.0) (Table S1 in Supplementary Appendix).

Variation of Antioxidant Capacity in Muscle Tissue As shown in Table 3 , the T-SOD activity and T-AOC of the breast muscle in the moderate EPE (0.9 g/kg) and high EPE (1.2 g/kg) groups showed an increasing trend compared to the control group ( p > 0.05).

The miR-222 agomir group showed an increasing trend, whereas the miR-222 antagomir group showed a decreasing trend compared with the model group (p < 0.05).

Results An increasing trend in the annual consumption of tetracyclines, β-lactam/β-lactamase inhibitor (BL/BLI) combinations, and carbapenems was observed ( P < 0.05).

The results showed that with increasing AAPH concentration, the carbonyl content of the proteins exhibited an increasing trend ( p < 0.05); SDS-PAGE pattern changes indicated that moderate oxidation (3 mmol/L AAPH) induced myosin aggregation via covalent bonds including disulfide, enhanced protein–protein interactions, and thus affected the gel strength of the DMPs’ heat-induced gels.

In comparison with the DSS model group, the pro-inflammatory cytokines TNF-α, IL-1β, IL-6, IL-12, and IFN-γ in the treatment groups showed a decreasing trend, and the anti-inflammatory factor IL-10 showed an increasing trend ( Table 5 , P < 0.05).

As shown in Figure 3B , the proportions of participants positive for aeroallergens and food allergen tended to decrease with age; however, an increasing trend was found from 0–10 to 11–20 for aeroallergens ( p < 0.05).

In community hospitals, the drug proportion showed an increasing trend before the intervention ( p > 0.05), while at the time of the intervention, a sudden decline occurred ( p < 0.001).

In addition, il-6 and il1-β are precursors of hamp ; therefore, the expression levels of hamp1 and hamp2 in the 0-R group showed an increasing trend ( p < 0.05).

3.6 Relative mRNA expression of muscle growth-related genes With the increases in HPM content in the feed, the expressions of Myf5 , MEF - 2c , MEF - 2a , MyHC , and FST first exhibited an increasing trend followed by a decreasing trend, reaching a maximum in the HPM3 group ( P < 0.05).

The prevalence of severe NAFLD showed an increasing trend with the increase in TXNIP quartiles (for all trends, P <0.05).

When treated with tetrandrine, there was an increasing trend in mRNA and protein expression of Talin-1 ( p > 0.05) and nephrin ( p < 0.05), compared with that in the OverTRP group, but this finding was not statistically significant among the three treatment groups (p > 0.05; Fig. 3 f, g, j, and k).

The relative abundances of dominant pathway modules related to carbon metabolism ( P < 0.001) followed an increasing trend, including citrate cycle, glycolysis/gluconeogenesis, pyruvate metabolism, and pentose phosphate pathway ( P < 0.05).