“an increasing trend”

Notably, the detection rate of mecA ranks highest across different months and shows an increasing trend.

A meta-analysis study in 2019 demonstrated an increasing trend in the prevalence and incidence of MS in Iran over time [ 6 ].

However, over the sample period, the peaks of the medical insurance system gradually widened, suggesting an increasing trend in regional disparities.

Despite being a relatively uncommon malignancy, the global burden of SCCA showed an increasing trend, with a rise from approximately 29,000 SCCA cases in 2018 [ 2 ] to over 30,000 cases in 2020 [ 3 ] reported globally.

In the results of this study, the overall content of EAAs showed an increasing trend.

The average indirect economic burden ranged from $6253.27 to $14766.34 from 2007 to 2016 showing an increasing trend, which was 1.67 to 2.46 times the annual per GDP (Table 2 ).

In the EPMT, compared with Ctrl mice, a significant difference was observed in the time spent in the open arms between the SCZ and SCZ-P mice; compared with the SCZ group, mice in the SCZ-P group showed an increasing trend; however, the difference was not significant (Fig. 1 b).

We observed an increasing trend in iso-butyrate production in the colon model exposed to amoxicillin/clavulanate without NDC supplementation (Fig. 7 ).

However, we observed an increasing trend in the use of macrolides and third-generation cephalosporins, highlighting that the use of some antibiotics is still a challenge and that there is an urgent need to evaluate and optimize antibiotic use in the patient population with COVID-19.

Moreover, between 2018 and 2022, our annual surveys on the breeding status of wild Chinese alligators in China revealed an increasing trend in nesting, egg laying, and hatching alligator numbers, with particularly notable growth in the past 2 years ( Fig. 5D ).

Due to the recent shortage of liver donors and increased mortality on the waiting list, there is an increasing trend to transplant elderly livers, steatotic livers, donation after circulatory death (DCD) livers, split livers and hepatitis virus-positive livers.

The protein expression of HNRNPC in SVF showed an increasing trend and significantly increased mRNA level compared to adipocytes in mice.

This is broadly consistent with the findings of [ 76 ], who found an increasing trend in the period 1960–2005 CE of 0.386 over the 45 years due to a more meridional pattern of circulation associated with global warming.

In contrast, the ASIR and ASMR of urological cancers in mainland regions other than Hong Kong, Macao, and Taiwan showed an increasing trend with higher GDPPC.

In addition to adult obesity, an increasing trend of childhood obesity is typical not only in Hungary but also in Europe; at the same time, the number of years spent in healthy conditions among adults is significantly lower in Hungary compared to Europe [ 10 , 11 , 12 , 13 ].

Across groups from “consistently low” to “consistently elevated” to “high-drop-high,” there is an increasing trend in the risk of preterm birth (8.5%, 13%, 22%), pre-eclampsia (5.8%, 9.4%, 43%), gestational hypertension (4.8%, 14%, 16%), and type 2 diabetes (3.5%, 7.5%, 14%).

The EAPC and its 95 % confidence interval (CI) were computed as follows: EAPC = 100 × e β − 1 An EAPC lower bound >0 indicated an increasing trend in disease burden, while an upper bound <0 signified a decreasing trend.

An increasing trend was defined as APC/AAPC >0, while a decreasing trend was defined as APC/AAPC <0.

4.2 Glargine U300 use and concomitant therapy The dose of Gla‐300 (total and daily) exhibited an increasing trend, peaking at Stage 3, 4 and 5 CKD indicating a potential association between reduced kidney function and insulin requirements.

Conversely, the self-harm incidence was more common in females, and showing an increasing trend for both sexes.

The annual publication count on PC and nanotechnology was basically on an increasing trend from 2004 to 2023, as depicted in Fig. 2 A, suggesting a rise in focus on the domain of PC and nanotechnology.

Additionally, the score for Factor 1 (sleepiness on rising) on the OSA-MA showed an increasing trend on week 4, and the score for Factor 2 (initiation and maintenance of sleep) increased significantly ( Figures 4C , D ).

3.1 Oxidative stress biomarkers The dynamic analysis of oxidative stress markers ( Figure 2A ) revealed an increasing trend in 8-OHdG levels during and after surgery in both groups.

Firstly, there is an increasing trend towards repeated exposure to the same content (Wrigley et al., 2012 ), or cross-institutional assessment in the form of a shared “national licensing assessment” which candidates have to pass before graduating (Allawi et al., 2016 ; Cuddy et al., 2017 ; Schuwirth et al., 2010 ).

There was also an increasing trend towards community-based ‘longitudinal integrated clerkships’ and curricula emphasising primary care (Association of American Medical Colleges, 2012 ; Condon et al., 2017 ; Cristobal & Worley, 2012 ; Hays, 2001 ; Hays et al., 2003 , 2019a , b ; Hurt & Harris, 2005 ; Lawson et al., 2004 ; Smego et al., 2010 ; Strasser & Lanphear, 2008 ; Strasser et al., 2009 ; Tesson et al., 2009 ; University of California Riverside, 2008 ).