Barely Significant
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“an increasing trend”

63,972 sentences · 63,972 papers · 107,686 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

An increasing trend of delayed childbearing has led to a notable rise in pregnancies among women of advanced maternal age (AMA), typically defined as age ≥35 years ( 8 ).This shift in maternal demographics has impacted the epidemiology of MHD, necessitating a deeper understanding of their burden and trends among reproductive-age AMA women.
The shift in T:B cell ratio in mice treated with pyrene corresponded with an increasing trend observed for the B cell population (absolute and relative) and a decreasing trend for T cells (relative) with the relative counts being significant for both populations in mice treated with ≥25 mg/kg bodyweight/day pyrene.
55 Specifically, there is a significant decrease in soluble UCH‐L1 protein levels but an increasing trend of insoluble UCH‐L1 levels in AD frontal cortex, 58 and soluble UCH‐L1 protein levels are inversely proportional to NFTs numbers in AD frontal cortex. 55 A recent study also reported that UCH‐L1 protein levels decreased in the cerebral cortex (superior frontal gyrus) of patients with late‐onset sporadic AD. 57 Therefore, in different brain regions and stages of AD, the regulation of UPS might be different, and it is crucial to investigate whether these changes are due to gene expression, protein degradation, or aggregation.