“an increasing trend”

Results From 2014 to 2023, Jiangxi reported 417,636 seasonal influenza cases (average annual reported incidence: 91/100,000), showing an increasing trend, with a slow increase from 2014 to 2021 (annual percentage change [APC] = 17%, 95% confidence interval [CI] = −17%–32%, p = 0.232) and a subsequent sharp rise from 2021 to 2023 (APC = 154%, 95%CI = 39–304%, p < 0.001).

The results showed that the median serum IgE level only showed an increasing trend without any statistical difference at the time of disease relapse ( P = 0.234, Fig. 5 a).

Only total DNA content of Ad-MSCs on RGD cryogels showed an increasing trend (1.25-fold, p = 0.234) during the 14 days of osteogenic differentiation ( Figure 4 A).

Indeed, as Figure 1B shows, an increasing trend in mean Cmax values were observed in the mycotoxin treated groups ( p = 0.238).

Spring precipitation showed an increasing trend, but there was no linear relevance (R 2 = 0.045, F = 1.381, P = 0.250; Fig 1C ).

An increasing trend was observed with Sm-MSCs for chondrogenic markers SOX9 (3.8-fold; P = .25), ACAN (2.3-fold; P = .25), COMP (2.6-fold; P = .25), and COL2A1 (19-fold; P = .25) ( Figure 2F ) as compared with SF-MSCs, as well as notable increases in the expression of SFRP4 (584-fold) and GDF5 (3.5-fold), which are both highly specific for synovial-origin MSCs 4 , 24 , 48 ( Appendix Figure A3 , available online).

This observation was also supported by the results presenting different prevalence in the collection year; for example, a statistically significant decreasing trend was observed in CHIKV (2014, 86.8%; 2015, 66.2%; 2016, 53.3%; 2017, 58.8%; p = 0.0004), whereas an increasing trend was observed in DENV (2014, 10.5%; 2015, 23.1%; 2016, 18.9%; 2017, 29.4%; p = 0.25).

mori IGF-II mRNA-binding protein ( BmIMP M ) showed an increasing trend in the ovary ( Masc : p = 0.2541, BmIMP M : p = 0.0183), fat body ( Masc : p = 0.2401, BmIMP M : p = 0.1052), and wing discs ( Masc : p = 0.0288, BmIMP M : p = 0.0057) ( Fig 3B ).

An increasing trend in the proportion of adults with hypertension treated and controlled to less than 130/80 mmHg (41.9–49.7%, p = 0.258).

Macaques with SIB showed enhancement of structural connectivity and functional connectivity The whole-brain structural connectivity (SC) strength in the SIB group exhibited an increasing trend ( P = 0.259) relative to that in controls (Fig. 6 A).

We observed that DNAm age displayed an increasing trend line ( P = 0.26, Fig. 2 A) in the IMR-90 cells after treatment with 100 nM cortisol for 4 h; however, DNAm age displayed a significant decrease ( P = 0.004) in the cells after treatment with 500 nM relacorilant for 4 h, a selective glucocorticoid receptor modulator that competitively antagonizes the effects of cortisol activity, as compared with the untreated vehicle or the cortisol treatment.

Using 17,664 radio-days for females, annual survival rates showed an increasing trend over the 3 years, but there was no difference among years (all z-tests had P > 0.26).

Although the PFS in the RP group showed an increasing trend compared with that in the regorafenib monotherapy group, there was no statistical significance (3.8 vs 2.4 months, p=0.262 Figure 3G ).

Results from these statistical tests revealed that SBT participants showed an increasing trend in their reporting of malicious messages ( b = 0.21, p = 0.263, Odds Ratio ( OR ) = 1.23, 95% CI [0.56, 1.76]) and a decreasing trend in their reporting of benign, professional networking messages ( b = −0.09, p = 0.516, OR = 0.92, 95% CI [0.70, 1.20]) during skills-based training.

Of 191 (55.7%) patients with a second cTnI measurement, 49 (25.7%) had an increasing trend, which was not associated with mortality (univariate HR = 1.39, 95%CI: 0.87−2.22, P = 0.265).

The incidence of NAIMIs showed an increasing trend since 2013 when posaconazole prophylaxis was approved in Korea [correlation coefficient ( r ) = 0.735, P = 0.265].

The incidence of GAS between pre-pandemic and post-pandemic periods were similar (2.62 vs 2.92 cases per 10.000 admissions, P = 0.71); however, an increasing trend was seen in the incidence of iGAS cases comparing the pre- and post-pandemic periods (1.85 vs 2.34 cases per 10,000 admissions, P = 0.27).

Mortality of patients with AIDS showed an increasing trend comparing the first with third quinquennia, from 20% to 29% ( P = 0.27).

Plant heights followed an increasing trend up to peak values in the 16 th week (12-50cm) (F = 1.5, df = 5, p = 0.27) and 17 th week (30 – 63cm) (F = 1.7, df = 5, p = 0.21) during the seasons 2023A and 2023B, respectively.

Whereas, in multivariable logistic regression analysis, we only found an increasing trend of mortality in group 4 (platelet ≥400 × 10 9 /L) (OR: 1.5, 95%CI: 0.73–3.09, P = 0.27).

Compared with the control groups, IMQ-treated groups had the following changes: 1) interleukin (IL)-17A, IL-23, and tumor necrosis factor (TNF)-α levels were raised significantly in both serum and lesional skin (all p < 0.001); 2) retinol levels in lesional skin increased slightly ( p = 0.364), but no change was evident in serum retinol levels; 3) STRA6 was upregulated in both lesional skin ( p = 0.021) and serum ( p = 0.034); 4) RBP4 levels were elevated in serum ( p = 0.042), but exhibited only an increasing trend ( p = 0.273) in lesional skin; and 5) proteins and enzymes that mediate retinoic acid formation and transformation were upregulated in lesional skin.

After July 2016, we observed an increasing trend in the monthly number of live births, with a level change of 12,859 (95% confidence interval (CI) –12,300 to 38,100) ( p = 0.277).

When the trabecular and cortical bone was analyzed separately, an increasing trend in BV/TV was noticed (+ 9.42 ± 7.31%, P = 0.28), however, no other differences was detected (Table 3 ).

In progressors, PTH levels showed an increasing trend, albeit insignificantly, at T0, compared to pre-transition points T-1 and T-2 ( p = 0.28 and p = 0.3 respectively, Fig 4C and 4D ).

Also, an increasing trend was demonstrated in stroke volume and stroke index, which increased by an average of 5.68 mL/m 2 (1.02 to 10.34; p=0.28).