We observed HLA‐E and CD19 exhibit an elevated trend, while PVR, CD276, and CD47 are reduced in the low TROAP expression group (Figure 5A ).
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“an elevated trend”
Sighted at
p<0.05
In the literature
As shown in Figure 5 , amino acids and organic acids accumulate in an elevated trend in the model group, while fatty acids accumulate in a decreasing trend. 3.9.
Specifically, seven FFAs, including four polyunsaturated fatty acids (PUFAs): arachidonic acid (AA; 20:4 n -6; Figure 3A ), linoleic acid (18:2 n -6), docosahexaenoic acid (DHA; 22:6 n -3) and α-linoleic acid (18:3 n -3), showed an elevated trend at Visit 1 and Visit 2.
Interestingly, this concentration was statistically significant in the eRA group (disease duration of less than a year), which was probably due to the intensive and prolonged immunosuppressive treatment of patients with aRA where there is only an elevated trend.