C-P turned such an adverse trend into a favorable one. 65.4 mg/kg and 32.7 mg/kg C-P reduced the levels of MDA, LDH, and NO and enhanced the level of SOD compared with I/R rats ( P <0.01).
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RESULTS The follow-up prevalence rate of adult diabetes status by quartiles of baseline ALT and GGT levels showed an adverse trend for both prediabetes ( P < 0.05) and diabetes ( P < 0.01).
However, an adverse trend was observed in terms of V20, V30, V40 and V50, and VMAT was slightly improved compared with f-IMRT for these parameters (P<0.05).
We observed an adverse trend effect among males ( p = 0.056) and a protective trend effect among females ( p = 0.073) in the verbal memory domain, although these observations did not reach statistical significance.
When additionally adjusting for the first-year rejection burden (0/1/≥2 antirejection treatment cycles), the CIT effect attenuated, and the rejection burden showed an adverse trend: ≥2 vs. 0: adjusted HR 8.29 (95% CI 0.93–74.01, p = 0.058); 1 vs. 0: adjusted HR 5.29 (95% CI 0.49–57.62, p = 0.172); CIT per 60 min: adjusted HR 1.07 (95% CI 0.98–1.17, p = 0.122; events n = 11; analysis set n = 24).
The development of grade I–II acute GVHD tended to lower the risk of NRM compared with no acute GVHD in PTCy (HR = 0.16, 95% CI = 0.02–1.36, P = 0.093) and CBT (HR = 0.55, 95% CI = 0.27–1.11, P = 0.093), whereas there was an adverse trend in MDT (HR = 1.95, 95% CI = 0.97–3.91, P = 0.059) ( Supplementary Table 6 ).
No significant favorable effect of screening was detected, although there was a favorable trend for non-fatal MI (RR = 0.61 [0.29 to 1.29], p = 0.20), and an adverse trend for stroke (RR = 2.11 [0.96 to 4.64], p = 0.06).
ORI only showed an adverse trend in LRFS, when exceeding 7 weeks ( P = .06).
In terms of long-term prognosis, our intragroup analysis showed that an excessive leaflet CV was indeed highly associated with the risk of all-cause mortality and rehospitalization for HF in Type 1 BAV (HR (95% CI): 2.525 (1.038–6.139), p = 0.033), and an adverse trend could also be observed in Type 0 BAV ( p = 0.082).
Four trials [16] , [17] , [29] , [33] reported hypotension outcomes (5,118 participants, with 76 versus 16 events) with more intensive BP control greatly increasing the risk of hypotension (RR 4.16, 95% CI 2.25–7.70, p <0.001) and showing an adverse trend towards severe hypotension (RR 2.19, 95% CI 0.03–164.77, p = 0.723) although the annual rate of severe hypotension was very low (0%–0.15%) [16] , [33] .
an adverse trendgold
Study year moderated the intervention effects on the time children spent sedentary and in light PA, with a favourable trend found in older children and an adverse trend in younger children.
an adverse trendgold
Additionally, as the model positioned the teacher further from the students, the scenario drives what appears to be an adverse trend with distance that can be observed in the linear fit in Fig. 6(b) .
an adverse trendgold
Among Chinese adolescents, an adverse trend in iCVH from 2004 to 2014 was observed, particularly among girls and younger age groups.
an adverse trendgold
Globally, age-standardized mortality rates for diabetes show an adverse trend, increasing by 3% from 2000 to 2019 [ 1 ].
an adverse trendgold
Additionally, the anti-PLA 2 R levels reflect disease activity, with an adverse trend in clinical symptoms according to the antibody levels.
an adverse trendgold
By contrast, [C 10 NA][Br] and [C 16 NA][Br] exhibited an adverse trend. 2.5.
an adverse trendgold
However, the ASMR for stomach cancer demonstrated an adverse trend over the 40-year period.
an adverse trendgold
On the contrary, the pubertal adolescents group showed an adverse trend, which may be attributed to a change in independence from the parents during this age and more pressure from peer and themselves[ 36 ].
an adverse trendgold
DOC showed an adverse trend to SOM, with the DOC content increasing from 2.91 g/kg to 4.68 g/kg between the rice TIL and JOI stages and then decreasing to 4.04 g/kg from the JOI to MAT stages, primarily due to the comprehensive utilization of DOC, pH increase, and input and SOM decomposition varying with rice growth [ 43 , 44 ].
an adverse trendgold
There was an adverse trend between the soluble and storage carbohydrates levels with an increase in light intensity or decrease in lighting duration in basil leaves (Fig. 4 C).
an adverse trendgold
With the increase in the concentration of Ca, the P, K, and Ca distribution rates of leaves first showed a decreasing trend and then an increasing trend, and roots showed an adverse trend.
an adverse trendgold
This suggests an adverse trend associated with these therapies.
an adverse trendgold
CD16/32 expression was obviously increased in the SE group at 24 and 72 hours post-SE compared to the SE+MCC950 group ( Figure 2A–E ), whereas CD206 expression exhibited an adverse trend, being dramatically decreased in the SE group at 24 hours ( Figure 2A, B and G–I ).
an adverse trendgold
However, the period effects of China showed an adverse trend during 2015-2019.
an adverse trendgold
The main results show that both temperature and Nusselt number decrease with the non-Newtonian physical parameter, while the local and total entropy generation rates exhibit an adverse trend, which means that non-Newtonian parameter can provoke the local entropy generation rate.