Barely Significant
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“almost reached statistical significance”

379 sentences · 379 papers · 424 search hits before verification · confirmed specimen

Sighted at

p=0.06

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Even with these limitations and a quarter of the study population without history of CV disease, treatment with exenatide almost reached statistical significance for primary endpoint MACE, and it’s encouraging that direction of CV outcomes was consistent with beneficial effects seen in previous trials.
However, although we failed to find a relationship between compliance with any particular guideline and vaccine uptake, using FFP2 or FFP3 as the only mask almost reached statistical significance, a behavior that could result from considerations of both personal and societal health benefits [ 37 ].
No other significant differences in clinical outcomes were found, but adjusted analysis of mortality almost reached statistical significance favoring aspiration based thrombectomy (cOR 0.94, 95% CI 0.79 to 1.12; aOR 0.82, 95% CI 0.67 to 1.00).
Interestingly, PSBM9 was not selected under our criteria but almost reached statistical significance in our study (FDR = 0.01 and log 2 Fold Change = 0.96, upregulated in the pro-immunogenic subgroup) which suggests that our biomarker filtering criteria could perhaps be reassessed in order to identify additional genes with potential as biomarkers.
On the other hand, as the present study was designed to locate the association between the suspected Zika virus during pregnancy and the delivery of a newborn with congenital microcephaly, further research with more statistical power is needed to draw definitive conclusions for the other signs, symptoms and exposures described in Table 1 that almost reached statistical significance (e.g. conjunctivitis and retro-orbital pain).
The negative association between PAPP-A concentrations and gestational hypertension, as observed in other studies ( 13, 19 ), almost reached statistical significance in our study (presumably the reason that it did not was due to insufficient statistical power in the lower number of pregnancies studied).