This is the first case of its kind in the UK, underlining a worrying trend both toward higher proportions of enteric fever caused by S. paratyphi (an organism for which no vaccine is available), and toward increasing loss of antimicrobial effectiveness against the organism in South Asia and elsewhere.
Finally, both facilities displayed high fluoroquinolone resistance rates—a worrying trend seen globally despite measures in place aimed at limiting their use.
However, an increasing prevalence of MDR Salmonella resistant toward clinically important antimicrobials such as fluoroquinolones and third-generation cephalosporins highlights a worrying trend toward Salmonella infections that are increasingly difficult to treat with antibiotics ( Jajere, 2019 ).
Although contamination levels are still considered suitable for recreational use according to World Health Organization (WHO) standards, the increase indicates a worrying trend.
Obesity has become established as one of the strongest risk factors for the development of DM and there appears to be a worrying trend that individuals with lower education levels and/or relative affluence are driving obesity rates rather than the reverse.
We observed a worrying trend of increased resistance of gut colonizers over time.
This is a worrying trend given that the incidence of diabetes in Kenya and Africa is rising [ 8 ].
Shortly before the confirmed local outbreak, demand for COVID-19 vaccine had slowed in months, presenting a worrying trend that could delay achievement of herd immunity.
The worldwide emergence of colistin-resistant strains of animal origin is a worrying trend, as colistin is considered a last-line antibiotic [ 36 ].
A relatively new negative attitude towards seniors is a worrying trend.
This may provide reassurance, as what might be a worrying trend upwards is shown to be consistent with the expected age-related increases for a healthy man of similar age and starting PSA level ( Latini et al , 2007 ; Pickles et al , 2007 ).
This is a worrying trend in narrowing the gender gap, warned by preliminary studies. 15 , 17 Also, in West Bengal, the distribution of AUD and TUD is higher in the urban metros than in rural or urban non-metros, in contrast to the national trend revealed by the NMHS and GATS-2 survey.
Discussion Despite cross-immunity among a vast majority of the global population [ 15 ], we are witnessing a worrying trend of constant Omicron sublineage re-infection in parallel with waning immunity [ 7 , 16 , 17 ].
Indeed, drug shortages have tripled in the last 6 years, while few have left the list, portraying a worrying trend [ 3 ], while the global nature of the problem has become increasingly dire [ 49 , 50 ].
However, the disaggregated picture shows a worrying trend, especially for those who are illiterate or are living in abject poverty.
However, there is a worrying trend towards a rapidly increasing incidence of BCC in the age group of population under 40 years, especially in women [ 6 ].
The latter conditions are to combat a worrying trend where large data consolidators invest in data providers with the promise of support for complex and hitherto expensive analysis but, once the analysis is complete, restrict access to the products of the analysis either behind firewalls or under use restrictions that limit application to only those that the consolidator considers viable business opportunities.
There is also a worrying trend for younger people to engage in suicide pacts made via the internet, a vogue that is now worrying countries in the West as well.
Several weeks in to the shutdown in Austria, physicians noticed a worrying trend: The strict stay-at-home order, as well as fear of contracting the virus, was apparently stopping patients from seeking timely medical attention [3] .
From the perspective of antimicrobial resistance, recent investigations have shown a worrying trend toward multidrug resistance (MDR) in S .
However, there is a worrying trend of increased drug resistance in T. gondii which may exacerbate the disease severity and result in treatment failure [ 2 ].
Amoxicillin resistance was noted at 14.3%, a worrying trend given that amoxicillin is a commonly prescribed antibiotic.
There are limited treatment options for MM, and relapse and developing resistance against treatment drugs is a worrying trend in MM ( Anderson et al., 2009 ).
The current third epidemic of ROP 7 is a worrying trend for developing nations.
Studies have shown that antidepressant use is widespread among medical students, indicating a worrying trend [ 13 , 14 , 15 ].