“a worrying trend”

The studies registered in PACTR show a worrying trend which shows that 55% of the trials have no funding while 23% of the trials are self-funded.

It is, however, a worrying trend that more recent publications compared to earlier work provide less information necessary for the reproduction, or to push the innovation of phantoms forward.

The observation of widespread resistance to pyrethroids particularly permethrin and deltamethrin in this study area confirms a worrying trend already well-documented across West and Central Africa.

A worrying trend in our results is the increasing resistance of Klebsiella spp. and its increasing occurrence as an etiological agent of UTIs.

A worrying trend shows that today’s older people have higher levels of frailty than previous generations [ 11 ].

These observations present a worrying trend of antimicrobial resistance in the East African region.

Traditional publishing houses turning to the dark side? We suggest that there is a worrying trend that practices common among predatory publishers are becoming increasingly common also among traditional publishers.

Although complete resistance to glycopeptides remains uncommon, the emergence of vancomycin-intermediate strains reported from southern India signals a worrying trend[ 51 ].

The simultaneity of risk behaviours reveals a worrying trend of increasing risk with age, highlighting the need for preventive interventions throughout adolescence.

Post-2019 trends highlighted regional disparities, with Low SDI regions showing a worrying trend of stagnation and gradual increase in several metrics.

Indian women are eleven times more likely to develop GDM and this is a worrying trend because it is associated with adverse pregnancy outcomes.

The loss of family physicians from the medical profession within South Africa was more than the loss to emigration, and this is a worrying trend.

138 Meanwhile, Staphylococcus aureus is known to be able to greatly increase its virulence by developing antimicrobial resistance, and indeed a worrying trend of increasing methicillin-resistant Staphylococcus aureus infections has been observed, 135 accounting for up to 7.5% of all infections according to a large IE database in Japan. 141 Several risk scores have been developed to predict risk of IE in patients with Staphylococcus aureus bacteremia.

In China, significant weight and height changes were observed among pre-primary children during school closures, indicating a worrying trend towards obesity [ 45 ].

Our results also show a worrying trend pointing to an increase in opioid procurement by Israeli HMOs in primary care, now estimated to be at over 90 OME per capita rates.

A worrying trend is the increased prevalence of non-nucleoside RT inhibitor (NNRTI) related mutations in newly diagnosed patients [ 3 , 5 ], as single NNRTI mutations, such as the frequently observed K103N mutation, can result in high levels of resistance against first generation NNRTIs [ 6 ].

A worrying trend was seen in the adaptation of malaria vector species to the urban environment.

1 , 2 Recent data from GLOBOCAN 2020 elucidate a worrying trend, placing CRC at the third spot in terms of cancer incidence, encompassing 10% of all new cancer diagnoses, while it stands second in causing 9.4% of global cancer‐related fatalities, irrespective of demographic divisions such as age and gender. 3 The disease exhibits significant variability, in

The low HepB VC observed in our study is a worrying trend, since this vaccine is part of the vaccine schedule in all the countries of origin included our study [ 22 , 23 ].

These figures highlight a worrying trend in which dental caries remains prevalent, particularly in developing countries where access to dental care is limited.

Unfortunately, data shows a worrying trend in 2019, before the pandemic, where 18.4 million children missed out on routine vaccinations globally [ 9 ] which increased to 24.4 million during the pandemic in 2021 and remained elevated at 20.5 million in 2022.

A worrying trend as revealed in a contemporary example by De Cassai et al .[ 16 ] is presented by the rather frequent phenomenon of the citation of retracted literature in regional anesthesia.

In the present work the prevalence of MF resistance was 62%, indicating a worrying trend.

Statistics have revealed a worrying trend regarding the disease demographics, highlighting a 2-fold increase in the incidence of lung cancer over the past 30 years [ 3 ].

Studies have shown that antidepressant use is widespread among medical students, indicating a worrying trend [ 13 , 14 , 15 ].