Of 6 loci previously associated with insulin resistance, here 3 also showed an association with HOMA2-IR and a trend towards significance for GDM2013 but not GDM1999 including SNPs rs7607980 in the COBLL1 gene [ 40 ], rs13389219 near GRB14 and rs10423928 in the GIPR gene indicating that some of the genetic basis seem to be driven by previously reported insulin resistance loci.
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“a trend towards significance”
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However, unlike previous studies which have found significant differences in dual task interference of step length and velocity between FOG and non-FOG participants, we only found a trend towards significance between groups.
Differences were considered to be statistically significant at p < 0.05, and 0.05 < p < 0.10 was considered to be a trend towards significance. 3.
Pulse wave velocity, a well-validated marker of arterial stiffness, has been reported to be significantly higher in CoA patients who were hypertensive on exercise-testing (>200 mmHg) compared to normotensive patients with a trend towards significance in patients who were hypertensive on 24-h ABPM [ 20 ].
The association with waist circumference and SBP resulted in a trend towards significance.
They described a significant positive correlation of CTC status with positive tumour resection margins and a trend towards significance with the presence of seminal vesicle invasion and extracapsular extension, predictive of poor response to RT.
While the only significant association across multiple neurodegenerative diseases was found for the AD group, a trend towards significance was noted for DLB.
Mann Whitney-U test suggested that TAD lat and TAD total were significantly different in the two groups, while TAD ap showed a trend towards significance.
In addition, proportional pain intensity has diminished significantly in the lumbar and pelvic area as well as a trend towards significance in the thoracic region 6 months after surgery.
However, there was a trend towards significance in ocrelizumab ( p -value 0.0523).
A value of P < 0.05 was considered statistically significant and shown in graphs with an *, a value of P < 0.1 was considered to be a trend towards significance and indicated with an #.
Two additional variables showed a trend towards significance, namely, HR > 90 beats per minute and presence of ascites (Table 3 ).
For all analyses, we reported association p values <0.05 to denote a trend towards significance and discussed metabolites with stricter significance of <0.01.
Notably, in this exploratory analysis, only the activation difference in the right striatum remained significant after whole-brain FWE correction at cluster level, and a trend towards significance after cluster-level FWE correction was observed in the left striatum.
Additionally, a change (with a trend towards significance) was observed at 120 min for N-oleoyl ethanolamine (OEA) and at 60 min for N-di-homo-y-linoleoyl ethanolamine (DGLEA) ( Table 6 ).
Between-group differences were found in sleep quality, alertness upon awakening, and a trend towards significance regarding mood upon awakening (see Table 3 ).
Dyslipidemia showed a trend towards significance, indicating a potential protective effect, but was not statistically significant (B = -0.448, p-value = 0.062, AOR = 0.639, 95% CI: 0.399-1.022) (Table 4 ).
There was also a trend towards significance for a positive correlation between the ICH and PHE volumes and the number of altered pathways as a continuous variable ( Figure 7 ).
A trend towards significance was observed in the BRAFV600E -mutated subgroup in the TCGA but statistical significance was not achieved.
Although p=0.052 is not significant, it is a trend towards significance.
A trend towards significance was observed for the association of preserved kidney function (OR 1.47, 0.99–2.19) and higher Charlson comorbidity index (OR 1.54, 0.97–2.44) with higher odds of SGLT-2i prescription.
Bacterial infection (OR = 2.48, p = 0.065) showed a trend towards significance, while depth did not significantly influence re‐amputation risk ( p = 0.96).
However, a trend towards significance was observed (OR 1.29; 95% CI 0.87–1.71; I 2 0.00%; Supplementary Figure 1 ).
The majority of the cortical structures examined (primary motor cortex, insular cortex, and DLPFC) did not show any significant differences between the RmTBI and sham injury groups, apart from a trend towards significance in the DLPFC.
A P -value < 0.05 was considered statistically significant, and 0.05 < P < 0.10 was considered to be a trend towards significance.