Logistic regression analysis showed that SARIFA positivity was a strong and independent predictor of DL‐based high‐risk status (OR = 8.44, 95% CI 4.46–17.2, p < 0.0001), whereas nodal‐positive status showed a trend towards significance (OR = 1.58, 95% CI 0.96–2.61, p = 0.073), and locally advanced disease (T3/4) was not significant (OR = 0.77, 95% CI 0.44–1.36, p = 0.368).
Differences in mean daily steps between income groups were no longer significant when controlling for sex; although there was a trend towards significance ( F (4,262) = 2.17, p = 0.073).
Diffusion parameters did not correlate with clinical outcome, with the exception of ΔADC (%), which showed a trend towards significance ( p = 0.073).
All patients from Group A (100%) demonstrated >1.5 FC in HLA-DR+CD38+CD8+ T cells in the peripheral blood compared with only 60% from Group B with a trend towards significance (p=0.074, figure 4A ).
Exploratory analyses showed the relationships of N1 percentage with mood disturbances and REM latency with self-reported freezing of gait, of which only the relationship of N1 percentage with depression score showed a trend towards significance after the correction ( r partial =.551, FWE- p = .074).
In detail, considering antibodies pattern of SSc patients, a significant correlation between ANA and PI3K expression ( p = 0.044) and between ANA and PDGFRβ ( p = 0.031) was observed, with a trend towards significance regarding to ACA and PDGFRβ ( p = 0.074) and ANoA and PI3K ( p = 0.079).
Blood mtDNA content was not significantly associated with any phenotype, although there was a trend towards significance for tibial dysplasia (0.23; P =0.074).
Male donor gender reached a trend towards significance (OR = 2.596 (95%CI 0.913–7.384; p = 0.074, intercept = − 0.37)).
There was also a trend towards significance to agreement with a longer time since the initial diagnosis ( p = 0.074).
Overall, there were 117 (79%) correct final assessments, showing a trend towards significance compared to the baseline (Chi‐square = 3.184, p = 0.074) (Table 4 ).
10.2%), the adjusted model showed a trend towards significance (adjusted HR 0.60, 95% CI: 0.35–1.05, p = 0.074) ( Table 3 ).
However, the interaction between clinical severity and psychological impact of COVID-19 showed a trend towards significance (F 1,115 = 3.245, p = 0.074), indicating that the link between the traumatic impact of the pandemic and depression may vary depending on clinical severity, although it did not reach robust statistical significance ( Table 2 ).
RESULTS: The frequencies of genotypes and alleles between infertile and fertile endometriosis groups in relation to the control groups showed a trend towards significance in infertile endometriosis group, P = 0.074; OR=0.79; CI=0.61 to 1.02.
Post hoc comparison showed that VO 2max was significantly lower for TR than that obtained during 30-15 IFT measured with a gas analyzer i.e., IFT K4 (PC = 6.1%, p = 0.007), but had only a trend towards significance when compared to the predicted value from the IFT result (PC = 4.4%, p = 0.074).
A trend towards significance was observed at day 7 (P = 0.074).
Moreover, RT maintained its role as an independent prognostic factor for poor PFS ( p = 0.002), while higher MAL levels exhibited a trend towards significance ( p = 0.074).
FeHex improved the body weights of rats and neuroscore at 0.225 mg/kg, while a trend towards significance ( p = 0.075) was seen with the corner test at 1 mg/kg.
The iAUC for cortisol did not reach significance in either group, with a trend towards significance for HA ( p = 0.075; see ESM Table 1 ).
In the multivariate analysis, PNI remained a significant independent predictor of worse PFS (HR: 2.83; 95% CI: 1.33–6.01; p = 0.007), while non-CR showed a trend towards significance (HR: 2.14; 95% CI: 0.93–4.95; p = 0.075).
Furthermore, the IP distance (mean male 10,80 ± 1,60; mean female 10,03 ± 1,09) revealed a trend towards significance ( P = 0.075).
Analysing data from in vitro drug screening of these cell lines, through the Genomics of Drug Sensitivity in Cancer project (GDSC; release 6.1 52 ), we found afatinib IC50 values to be widely distributed among HER2 mutant cell lines, with a trend towards significance with afatinib sensitivity when compared with HER2 wild-type cancer cell lines (P=0.075; 9 HER2 mutant cell lines tested).
For practice scores, no statistically significant associations were identified across any demographic variable, although a trend towards significance was noted for Makana municipality relative to Raymond Mhlaba (OR = 2.867; 95% CI: 0.948–8.665; p = 0.075) and for farmers owning more than 31 cattle relative to the 1–10 reference group (OR = 3.272; 95% CI: 0.890–12.025; p = 0.119).
The primary factor associated with complications was extended resections (OR:15.33, 95% CI:1.566–150.141, p = 0.019), while vascular involvement showed only a trend towards significance in the multivariable analysis ( p = 0.075; Table 4 ).
There was no significant effect of reduced CYP3A4 activity, but there was a trend towards significance (mean difference: 6.242; 95% CI: −0.612, 13.095; p = 0.0751), where reduced metabolisers reported more adverse drug reactions than normal metabolisers.
For TMEV injection there was a trend towards significance (F (1,25) = 3.431, p = 0.0758).