“a trend towards significance”

This approach showed a trend towards significance [r(45) = − 0.28, p = 0.06], but needs corroboration on an independent dataset.

Univariate analyses showed a significant association with reduced disease-free survival (DFS) (p=0.01), and a trend towards significance for overall and progression-free survival (p=0.06 and p=0.05, respectively).

Of the 12 markers evaluated, the median unstimulated, antigen stimulated, or antigen-specific levels of seven (IFN-α2, IL-1Ra, IP-10, sCD40L, VEGF, MCP-3, IFN-γ) were either significantly different between the two groups or showed trends ( Table 2 ): the unstimulated levels of IFN-α2 and IL-1Ra were significantly higher (p<0.05) in children without TB disease, while the median unstimulated levels of IP-10 and sCD40L were significantly higher in those with disease, with the difference in the unstimulated levels of VEGF (higher in TB) and MCP-3 (higher in non-TB) showing a trend towards significance (p = 0.06 and 0.07 respectively) ( Table 2 ).

AA+AG the difference in overall survival showed a trend towards significance with rates at 5- and 8-year of 33.3% and 33.3%, 74.6% and 66.8%, respectively (p = 0.06) ( Fig. 2 ).

There were higher median SWE velocities measured pre‐ to post‐exercise in the group of healthy volunteers ( P = .01), but not among the CECS patients (although there was a trend towards significance; P = .06).

There was also a trend towards significance for the language inclusion variable (p = 0.06).

There was a trend towards significance for progressive ischaemia in those with IHD (OR 5.07, 95% CI 0.90–29.69, p = 0.06) and ‘triple positive’ aPL (OR 2.90, 95% CI 0.89–9.70, p = 0.08) (see Supporting Information ).

Unstable patients had a significantly lower mean FEV 1 % predicted (69.7% v 62.4%; p = 0.016), worse mean SGRQ score (40.1 v 50.0; p = 0.019) and mean CAT score (14.0 v 21.0; p = 0.006), and higher mean CRP levels with a trend towards significance (3.0 v 4.5; p = 0.06).

A trend towards significance was found for real excitatory HF rTMS or iTBS vs sham in reducing anxiety at the end of treatment (MD = − 0.36; 95% CI − 0.73, 0.02; p = 0.06), but not at 1-month follow-up.

The reduction in number of blood meals taken was significantly different for PR mosquitoes (p = 0.02), with a trend towards significance in the NO group (p = 0.06).

A trend towards significance ( p = 0.06) was found for the gender and for the interaction between Gender and Area ( p = 0.06).

3d ) showed higher scores for perceptual abilities ( t (36) = 2.28, p < 0.05), and musical training ( t (34.1) = 1.80, p < 0.05) than patients with NPR; a trend towards significance was found for the Gold-MSI global index ( t (32.5) = 1.61, p = 0.06).

Within the group of preterm children, we found significantly higher levels of GM-CSF in preterms with impairment ( p < 0.01) and a trend towards significance for Gal1 and TRAIL ( p = 0.06 and p = 0.06 respectively) when compared to preterms without impairment.

Pairwise t -tests revealed a trend towards significance for the VC × VR comparison ( p = 0.0603; M diff = − 20.5) and a significant p -value for the VR × FTF comparison ( p = 0.0255*; M diff = 22.40).

A statistically significant difference was found between AA and TT genotypes (p = 0.0024) and a trend towards significance between TT and AT genotypes (p = 0.0609) (Fig. 1 ).

At the post hoc , we observed a significant score reduction after anodal tDCS of the more-affected M1 as compared to the sham session ( p = 0.023); a trend towards significance between the post-anodal and the baseline session ( p = 0.061) was also shown.

Complementary, a trend towards significance was demonstrated for the relationship between the ARWMC total score and the MDS-UPDRS-III ( β = 0.289, 95% CI − 0.074–3.131, p = 0.061) considering age, disease duration and the Charlson modified comorbidity index as covariates.

SN ANOVA test identified significant effects of drug treatment on the levels of p-Akt ( F 3, 21 = 4.243, p = 0.020) and the ratio of p-Akt/Akt ( F 3, 21 = 4.243, p = 0.020) in the SN; ANOVA analysis also indicated a trend towards significance on the levels of p-GSK3β ( F 3, 20 = 2.946, p = 0.061).

Finally, there was a trend towards significance for the 3-way interaction including the quadratic component (F(1,13) = 3.54, p = 0.061), which could be explained by a larger active vs. sham decrease of the (negative) quadratic coefficient for rhythmic than for sham stimulation (p < 0.05; CI = [−0.26 −0.03]; d = 0.76; B U[−0.10 0.24] = 2.26; both active vs. sham differences being significant when tested separately, p < 0.01; for rhythmic: d = 1.34; for random: d = 1.14).

There was not a statistically significant decrease in PTV coverage, although there was a trend towards significance (p=0.061).

2) with a trend towards significance ( P = 0.061).

Pairwise statistical comparison of the magnitude metric revealed a trend towards significance between placebo/moderate doses (paired t-test: p = 0.061) in the go-only blocks, with low alcohol dose showing a larger magnitude metric than placebo (Supplementary Fig. 5 a).

Correlation of CRP with clinical and laboratory variables CRP level, inflammation biomarker indicating the risk of atheroma plaque formation [ 22 ], was significantly correlated with age ( r = 0.194, p = 0.043), obesity ( r = 0.225, p = 0.022), and HbA 1c ( r = 0.154, p = 0.005), indicating a trend towards significance with Lp(a) ( r = 0.295, p = 0.061) in the patient group.

In our study, both factors were not independently prognostic for survival in multivariable analysis, although age showed a trend towards significance both for PFS (p = 0.061) and OS (p = 0.069).

IABP usage after 24‐h symptom duration demonstrated a trend towards significance in association with higher mortality (55% vs 38%, p = 0.061; Table S3, Electronic Supplementary Material).