In multivariable modelling, adding in all the factors that were individually associated with out-of-control asthma, only annual family income <$50,000 was significant for children, although obesity showed a trend towards significance ( P =0.06) and for adults family income <$50,000, smoking and obesity remained jointly significant ( Table 3 ).
Following initiation of anti IL-5 therapy, there was no statistically significant difference across the three therapies except at 3–6 months, where this was a trend towards significance ( p = 0.06) ( Figure 1(a) –( e )).
This grouped chromatin pathway analysis showed enrichment for more genetic alterations among MBM compared to PCM (23.4% v 12.3%, p = .002); however, there was only a trend towards significance when comparing MBM to ECM (23.4% v 16.2%, p = .06).
Despite not reaching statistical significance, our results revealed a trend towards significance in SHAPS assessments of anhedonia ( P = 0.06).
For the SBM informativity rate, the influence of the center and the incubator/medium used did not show statistical significance, although the impact of the clinic showed a trend towards significance ( p -value = 0.06 vs. p -value = 0.24).
There was a trend towards significance between groups in pre-treatment scores on the DASS-21 ( F 2, 128 = 2.83, p = .06), and no significant differences between CO, CL and Control groups in pre-treatment scores on the GAD-7, PSWQ, PDSS-SR, SIAS-6/SPS-6, PHQ-9 or SDS ( F 2, 128 range = .07 – .79, p range = .45 – .94).
Analysis of synchronization variability as determined by the standard deviation of tap-to-tone asynchronies revealed a trend towards significance of factor time ( F (1, 17) = 3.91, p = 0.06), while neither stimulation ( F (2, 34) = 0.45, p = 0.64) nor the stimulation x time interaction were found to be significant ( F (2, 34) = 0.048, p = 0.91).
There was a trend towards significance for feeling surprised, F (2, 320) = 2.86, p = .06, η 2 p = .02.
Motor scales analysed across the three groups showed a trend towards significance ( p = 0.06, n = 102); exploratory post hoc pairwise comparisons could not confirm significant differences.
There was a trend towards significance for the incidence of seborrhea, which was more common in the administrative/sales population ( p = 0.06).
A subsequent model included mood stabilizer as an additional covariate; a trend towards significance, with greater anti-anhedonic response associated with lithium than valproate was observed ( F (1,57) =3.57, P =0.06).
This increase in colon weight showed a trend towards significance ( P = 0.06) in the 5-FU + PBS treated animals in comparison with saline control animals (Table 3 ).
There was a trend towards significance for progressive ischaemia in those with IHD (OR 5.07, 95% CI 0.90–29.69, p = 0.06) and ‘triple positive’ aPL (OR 2.90, 95% CI 0.89–9.70, p = 0.08) (see Supporting Information ).
Male gender exhibited a trend towards significance (OR 4.6, 95% CI: 0.94–22.12, p = 0.06), and haemoglobin appeared as a protective factor (OR 0.76, 95% CI: 0.42–0.94, p = 0.026) ( Table 2 ).
However, a trend towards significance was noted for the DI parameter (p = 0.06).
Similarly, patients predicted to have LRR had poorer overall survival, where this only reached significance for the combined model ( p < 0.01) although a trend towards significance was observed for a model using only radiomics features ( p = 0.06) (Figure 4B ). 4.
When individual variables from the Khorana score were subjected to univariate and multivariate analysis in our cohort, the WCC was the only variable that retained predictive significance, with a higher WCC at MM diagnosis showing a trend towards significance in univariate analysis ( p = 0.06) for predicting VTE.
A trend towards significance was found between ADC kurtosis and TRG ( ρ = − 0.40; p = 0.06), between SUV kurtosis and TRG ( ρ = − 0.40; p = 0.07) and between SUV kurtosis and N stage ( ρ = − 0.39; p = 0.07) (Tables 2 , 3 , 4 ).
The 30-day mortality showed a trend towards significance in patients > 50 years of age compared with those aged ≤ 50 years (35.48% vs. 7.94%, p = 0.06) [Figure 2 ].
Of the 12 markers evaluated, the median unstimulated, antigen stimulated, or antigen-specific levels of seven (IFN-α2, IL-1Ra, IP-10, sCD40L, VEGF, MCP-3, IFN-γ) were either significantly different between the two groups or showed trends ( Table 2 ): the unstimulated levels of IFN-α2 and IL-1Ra were significantly higher (p<0.05) in children without TB disease, while the median unstimulated levels of IP-10 and sCD40L were significantly higher in those with disease, with the difference in the unstimulated levels of VEGF (higher in TB) and MCP-3 (higher in non-TB) showing a trend towards significance (p = 0.06 and 0.07 respectively) ( Table 2 ).
The seroprevalence of FIV infection was not significantly different between ‘healthy’ and ‘sick’ cats using the aforementioned definitions (14% vs 16%; P = 0.17), although when cats classified with dental disease were excluded from analysis there was a trend towards significance ( P = 0.06).
Significant age-related differences were observed in knowledge of maximum recommended sugar intake (χ2=6.24, p = 0.04), fluoride use (χ2=19.12, p < 0.01), and a trend towards significance for the recommended age for first dental visit (χ2=7.71, p = 0.06) and sealant application (χ2=5.81, p = 0.05).
Unstable patients had a significantly lower mean FEV 1 % predicted (69.7% v 62.4%; p = 0.016), worse mean SGRQ score (40.1 v 50.0; p = 0.019) and mean CAT score (14.0 v 21.0; p = 0.006), and higher mean CRP levels with a trend towards significance (3.0 v 4.5; p = 0.06).
Low INSM1 gene expression was associated with shorter overall survival in the entire case series ( p = 0.0017) and with a trend towards significance in EPNEC, only ( p = 0.06).
Health insurance status and having a usual place of care showed a trend towards significance; participants who were insured (64 vs. 50%; P = 0.06) and had a usual place of care (62 vs. 48%; P = 0.06) were more likely to be up-to-date with CRC screening compared to those who were uninsured and did not have a usual place for care.