CD226 SNP rs763361 was significantly associated with SSc-ILD in a meta-analysis study of three European populations, with a trend towards significance when each population was analysed separately [ 14 ].
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Furthermore, a higher number of vertebral body levels spanned by the abnormal vasculature showed a trend towards significance, and has previously been correlated with the degree of myelopathy in patients with SDAVF [24] .
If a patient with pervasive developmental disorder is excluded from the analysis, there is a trend towards significance in the number of total neurites in patients with SCZ but there is no statistical difference when only medicated patients are analyzed (Supplementary Table S16 ).
There was a trend towards significance for the association between a time to diagnosis greater than 12 months from symptom onset and an increased probability of the outcome (Table 3 ). 3.6 Qualitative Findings From the qualitative analysis of caregivers' proposals to improve the care of PLwD in their area, some key themes emerged more frequently (Figure 3 ).
In a direct comparison of the system and SCP estimations for each meal, the system showed a significantly better performance for energy and CHO estimation, while it showed a trend towards significance for protein, fat, and fatty acid estimation ( Figure 9 b).
In particular, Martin-Blanco and colleagues, investigated the association between NR3C1 methylation status, history of childhood trauma and clinical severity in blood samples of BPD subjects, showing an association between NR3C1 methylation and childhood trauma, in the form of physical abuse, and a trend towards significance for emotional neglect [ 88 ].
While there was no statistically significant difference in antibiotic selection, the teaching session demonstrated a trend towards significance in improving therapeutic reasoning as defined by the PEST strategy.
We found a strong association between PD-L1 protein expression with high tumor grade (p value = <0.001) and with the development of distant metastasis on follow up (P=0.037) There was a trend towards significance in the relation between PD-L1 and both patients’ age and tumor stage.
The addition of bevacizumab to a chemotherapy regimen was well tolerated in this elderly population, with only a trend towards significance for hypertension (Table 2 ) in patients treated with bevacizumab; the incidence of all other adverse events was comparable with those receiving chemotherapy alone.
There were significant group differences [F(3,936) = 6.45; p = 0.0003] with severe OSA group showing the steepest relationship with a trend towards significance, and no OSA group shows a significant but weak association and mild/moderate groups showing no association (Fig. 2 C).
Combined buckle with vitrectomy had a trend towards significance for further retinectomy rate.
Consistent with the univariate analysis, the multivariate Cox analysis confirmed that older age (>65), female sex were significant negative prognostic factors, with N3 status showing a trend towards significance ( Figure 3E ).
Univariate (Chi square) analysis of histology of the tumour with the failure pattern showed a trend towards significance (P value-0.048).
Although the p -value suggests a trend towards significance, it does not reach the conventional threshold of 0.05, indicating that the effect of “strain” may not be statistically significant.
Also, there was a trend towards significance for early age at onset as a neurodevelopmental outcome predictor in the present study similar to the Finnish cohort [ 9 ].
There was a trend towards significance in the age-adjusted model for exposure to stressors related to safety in the community and adolescent BMI with greater exposure to this stressor associated with increased adolescent BMI ( β = 0.90(0.46), p =0.05).
Patients who received the prosthesis secondarily had a higher mean CPPS and a lower mean AVQI; this difference does not reach statistical significance but still has a trend towards significance ( Table 5 ).
A trend towards significance was observed in average age; the average age of the Foreign cohort was 5 years younger than the Familiar cohort.
For the 2-Back task (p = 0.06), there was a trend towards significance for average reaction time (RT) with student grade point average.
Among individuals with abnormal blood glucose levels, we observed a significant association between OBS and retinopathy in crude model, while the adjusted model showed a trend towards significance.
Except for a trend towards significance in the myocardium, we did not observe any relevant associations between PET-based tumor burden and normal organs.
Seasonal effects on stress indices Based on models containing season as the sole explanatory variable none of the main hormones representing HPA-axis activity, i.e., cortisol, cortisone or corticosterone showed differences in mean levels, except for a trend towards significance in the cortisol/cortisone ratio (Table 1 ).
Regarding significance testing, the item “level of anxiety in relation to playing Auskick” demonstrated a trend towards significance using the Wilcoxon signed rank test.
A trend towards significance was seen between the maximum lysis of target cells and the number of antibodies bound per cell at the antibody concentration leading to maximum lysis as well as between overall antibody binding and ADCC, defined by area under the curve (Fig. 6 c, d), suggesting that the level of antibody binding could be an important determining factor for the level of cell cytotoxicity [ 53 , 54 ].
Intra-group “CVR” (ρ) and intra-group “no_CVR” comparisons (ρ) The vascular density VD DCP , compared to the vascular density VD SCP , was significantly more strongly correlated with circulatory times FA AT , FA startLF and FA endLF ( p < 0.05, respectively, and with a trend towards significance for FA endLF in the no_CVR group), Table 2 .