Barely Significant
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“a trend toward significance”

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Compared with women who received a VKA regimen, the average risk of an adverse maternal event was significantly higher among women who received an LMWH regimen (RAR: 3.1; 95% CI: 1.3 to 7.5) or a regimen of UFH and VKA (RAR: 3.1; 95% CI: 1.5 to 7.4), with a trend toward significance in women who received a regimen of LMWH and VKA (RAR: 3.2; 95% CI: 0.9 to 8.8) ( Figure 4 ).
116 , 117 In early dcSSc, abatacept failed to improve skin score, though it showed a trend toward significance as well as manageable AEs. 118 In contrast, numerous published cases exist for the use of abatacept in patients with morphea and show promise for future potential large‐scale trials. 119 , 120 , 121 A retrospective compilation of eight cases of juvenile morphea showed no progression
Upcoming treatments for morphea.
Immun Inflamm Dis · 2021 · PMC8589364
We also looked at whether the observed difference in OS could be explained by differences in completion of all four cycles of ipilimumab or in whether any ICI was resumed after colitis and found no significant difference between moderate and severe colitis ( Table 3 ); however, given that there was a trend toward significance for both of these factors we conducted a multivariable Cox proportional hazards analysis (MVA) with completion of all four cycles of ipilimumab, resumption of ICI after colitis and severity of colitis, and only colitis severity was shown to have a significant effect on OS (HR 7.58, P = .002).
However, a trend toward significance was seen for the direct messaging campaign to have a lower percentage of participants identifying as white, to have a greater percentage identifying as Hispanic or Latino, to have an education above high school, and to have a higher income (White: 78.1% vs. 87.1%, p = 0.084; Hispanic or Latino: 3.5% vs. 0%, p = 0.072; Education: 89.5% vs. 81.9%, p = 0.063; Income: $112,967 vs. $91,064, p = 0.081).