Barely Significant
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“a trend toward significance”

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In the literature

a trend toward significanceP = 0.0571.1× alpha
However, the success rate for afferent limb intubation on the first attempt for Operator A’s first (63.2 %) and last (80 %) 20 cases was higher than for Operator B (50 %); with a trend toward significance between the last 20 cases of Operator A and Operator B ( P = 0.057).
a trend toward significanceP =0.0571.1× alpha
33 Finally, a retrospective analysis evaluated the value of EGFR gene copy number assessed with fluorescence in situ hybridization (FISH), as a predictor of outcome in 557 evaluable patients; although a positive FISH does not qualify as a predictor of outcome with statistical significance, a trend toward significance was observed for both PFS (interaction P =0.057) and OS (interaction P =0.066), and the addition of necitumumab in the FISH-positive population resulted in an HR equal to 0.71 for PFS (95% CI=0.52–0.97) and 0.70 for OS (95% CI=0.52–0.96). 34 Safety profile The different trials involving necitumumab allowed the investigators to collect meaningful data about its safety profile and the drug-related adverse events.