The test statistic comparing time effects between MPTP and control groups yielded a one-sided p -value of 0.062 ( B = 5,000 permutations), showing a trend toward significance that suggests the observed pattern of miRNA changes in MPTP-treated animals may reflect genuine biological effects rather than random variation.
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“a trend toward significance”
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The oral route resulted in significantly greater cocaethylene formation than smoking (34% ± 20% versus 18% ± 11%, respectively) and showed a trend toward significance for greater formation of cocaethylene compared to even intravenous administration.
A p -value below 0.05 was considered indicative of statistical significance, whereas a trend toward significance was defined as 0.05 ≤ p < 0.10. 3.
The results revealed that AP showed a trend toward significance, while VJ remained significantly associated with FD.
A two-sided p < 0.05 was considered statistically significant, whereas a value of 0.05 ≤ p < 0.10 was interpreted as indicating a trend toward significance.
Thus, the final model presented here can accurately describe the data but only shows a trend toward significance, likely due to the relatively large variability in the data compared to a small set of only 16 participants being evaluated.
Although only a trend toward significance in our study for racial disparity in COVID-19 was observed, a large systematic review involving 50 studies from the United States and United Kingdom concluded that individuals of black and Asian ethnicities have a higher risk of contracting COVID-19 in general, and more specifically, Asians were at a higher risk of hospital admission and death ( Sze et al., 2020 ).
The increase in the burden of p409–410-positive aggregates in cells transduced with CP fibrils showed a trend toward significance (Fig. 6f ).
The difference in the number of BM showed a trend toward significance but did not reach statistical significance ( p = 0.086).
Atrophy of the caudate presented a trend toward significance. 67 In spite of variability within the literature, the most frequently observed regions of atrophy in LLD are the frontal lobe, limbic system, basal ganglia, and thalamus. 68 - 69 Within the frontal lobe, atrophy has been observed in the OFC, 68 , 70 - 74 and the anterior cingulate cortex (ACC).
Multivariate ANOVA on the log ratio state 3/state 1 yielded a trend toward significance for wild-type vs.
Refugees with PTSD had higher BDI scores with a trend toward significance.
130 No strong association was observed between smoking and DR in people with T1D, though there was a trend toward significance between smoking and incidence of retinopathy among people with T1D ( P value 0.052), leading to the conclusion that smoking is not likely to be an important risk factor for DRD. 130 Similarly, in a study of 201 patients with T1D, smoking was not associated with PDR over 25 years. 129 However, in th
3b ), with the fourth showing a trend toward significance ( r = 0.68, P FDR = 0.07, P uncorrected = 0.04).
Although a trend toward significance was observed for lesion sites, only FNA and benign final diagnoses were independent factors in multivariate analysis.
Post hoc analyses using t tests for paired samples with Bonferroni correction (α = .05/6 = .008) showed a trend toward significance when the average NA score measured during baseline measurement ( M = 22.91, SD = 7.79) and the one measured after the neutral stimulus ( M = 19.98, SD = 4.82), with the baseline score was higher, t (42) = 2.60, p = .01, Cohen’s d =.40.
KEGG pathway enrichment analysis revealed that PPARGC1A and TBC1D1 genes were enriched in the AMPK signaling pathway, a crucial pathway in muscle oxidative stress, showing a trend toward significance with a corrected P -value of 0.063 ( Fig. 3 and Table 5 ).
This frequency showed a trend toward significance in AHI individuals and was significantly higher in CHI individuals compared to HC.
Along with sex, the latter two variables were included in multivariate analysis due to a trend toward significance.
After correcting for possible false discovery rate, YMRS remained significantly associated with IS, RA, CQ with a trend toward significance with PSQI.
No significant behavioral deficits in fear conditioning or Morris water maze were observed at any time point, but a trend toward significance was found in cued fear conditioning at 12 weeks after injection.
There was a trend toward significance in long-acting injectable (LAI) medication administration/overseeing administration between those with PA compared with those without PA (13.5% vs 6.8%, respectively, P = .062).
There was a trend toward significance for anosmia/dysgeusia (odds ratio 1.58; p -value 0.0847), while coefficients for time point since RT-PCR positivity, dyspnea and coughing were not significant in the model ( Table 2 and Figure 2B ).
HIV-infected individuals had higher PD-1 (adjusted β = 0.12, p = 0.034) and TIM-3 (adjusted β = 23.15, p = 0.052) levels, with the latter showing a trend toward significance.
However, remission rates showed a trend toward significance, favoring TGTG (TGTG = 47.8% vs.