The mean changes in the blood count at irAE incidence were not significantly different before the first dose of ICI, but the difference in rise in ANC (by 5.29, P = 0.07), NLR (9.4, P = 0.09), and WBC (5.1, P = 0.09) had a trend toward significance.
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“a trend toward significance”
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The lack of a significant increase in the two remaining subdomains, Risks and Signs, may be due to lack of sufficient power, especially since there was a trend toward significance.
There were no differences between groups for individual microvascular complications, although there was a trend toward significance for microalbuminuria (Table 3 ).
Additionally, our study found a trend toward significance for monthly income as a predictor of depression level, indicating that financial stressors may also contribute to the development of depression.
The ANOVA test with p -values between 0.05 and 0.10 was considered as a trend toward significance. 3.
While factors such as age, sex, tumor location, cN (lymph node), did not appear to have a statistically significant effect on the occurrence of stoma complications, there were factors that showed a trend toward significance.
Despite high inter-rater reliability, the difference in capsular contracture rate between prepectoral and subpectoral cohorts was unable to achieve significance for each evaluator; however, given the result of the combination group, we anticipate a trend toward significance with a larger sample.
Nevertheless, while analyzed as LC risk categories used to define high and low risk patients, it showed barely a trend toward significance in trichotomous analysis and lost its predictive value when analyzed as dichotomous clinical categories (high vs. low risk) ( Table 4 ).
UHR subjects exhibited longer durations of excursions in the CAP 2 state (right anterior insula/DMN co-activation), and also, with a trend toward significance, larger counts.
Notably, there was a trend toward significance in a reduction of GluA2 levels ( Fig. 9 K), and a significant reduction in GluN1 levels, both in stressed males compared to sex-matched controls (Fig. 9L).
Lower Gleason categories and perineural invasion showed only a trend toward significance in the multivariable analysis, suggesting that their predictive effect may be attenuated by other covariates.
All statistical tests were two-tailed; P <0.05 was considered statistically significant, whereas 0.05≤ P <0.2 was considered a trend toward significance to increase the sensitivity for detecting potential selection bias.
This increase in TNFα was statistically significant in patients with HR-positive and TNBC subtypes, and showed a trend toward significance in HER2-positive patients ( Figure 5 C).
A trend toward significance was noted in the theory of mind (Hinting Task) within the salient task.
The separate analysis of the two hemispheres did not show a statistically significant change in these two EEG frequency bands, with only a trend toward significance.
A sensitivity analysis to investigate correlations between treatment attributes (scored out of 100 points across a total of 16 attributes) showed a trend toward significance for OS and DCR when used alone in the regression model with patients’/caregivers’ role in treatment decisions (agree vs disagree) as a separate metric.
Although occupation showed a trend toward significance, it did not reach the threshold.
Nevertheless, the CToM training does not seem to generalize its impact on the advanced ToM tasks, the Strange Stories, and the Faux pas test, for which we found a trend toward significance.
However, the medium effect size and directionally favorable confidence interval (95% CI: 0.21 to 3.02 km/h) suggest a trend toward significance, which warrants cautious interpretation and further investigation.
In this study, therapy dose and therapy intensity reached significance or a trend toward significance in correlation with changes in motor network LI ( Table 4 ; Figure 5 ).
In the univariate analysis, the length of stay in hospital (odds ratio [OR], 2.77), operative time (OR, 2.74), and amount of time spent on treatment/surgery (OR, 15,610.9) were found to be significant factors, whereas blood loss (OR, 1.20) only showed a trend toward significance.
Nevertheless, to our knowledge, our study is the first to discover the role of CD8 + CD28 − T cells in immune responses and AEs, and these data with a trend toward significance were determined from only a simple peripheral blood examination.
There was a trend toward significance, but it did not reach statistical significance ( p = 0.1).
In addition, the task condition was associated to a higher proportion of time spent in the state 4, in comparison to both rest conditions, with a trend toward significance.
Maternal adverse outcomes were less common among those with UC, with a trend toward significance (OR 0.583, 95% CI 0.310-1.097), and those age 40 or older at delivery were significantly more likely to experience maternal adverse events (OR 3.896, 95% CI 1.339-11.337).