As shown in Figure 4 , no statistically significant differences were observed, which was consistent with the results from the Cox regression analyses, although certain variables exhibited a trend toward significance.
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“a trend toward significance”
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Significance was established at a level of P < 0.05, and a P value between 0.05 and 0.10 is considered as a trend toward significance.
In the treated group, the reduction in EPO doses showed a trend toward significance and the reduction in ERI was significant; in contrast, in the control group both parameters showed insignificant changes.
p Values of the mediating path “intervention–bacteria–CMFs” less than 0.05 were considered significant to identify precise and robust results, meanwhile p values for the mediating path “microbiota–metabolites–CMFs” less than 0.1 were considered a trend toward significance to uncover more insightful findings.
The decrease in the left lateral temporal cortex (p = 0.08, from 0.127 to 0.067) showed a trend toward significance, but did not reach statistical significance, while changes in the right lateral temporal cortex (p = 0.74) and left entorhinal cortex (p = 0.29) were not statistically significant.
A history of lung radiation combined with ICI therapy showed a trend toward significance.
While the increase in estradiol concentration during the follicular phase was not associated with any reflex properties, a significant effect emerged during the luteal phase, as well as a trend toward significance for estradiol × progesterone effect.
Notably, there was a trend toward significance for these metrics in the higher-risk populations–namely, those with a PSA value of >10 and a Gleason score of 7 or higher.
In the fully adjusted regression model, HAM-A showed the numerically largest standardized coefficient (β = −0.055; p = 0.064), representing a trend toward significance, while HDRS-17 did not individually reach statistical significance (β = −0.043; p = 0.147); cognitive impairment had negligible independent effects (β = −0.001; p = 0.947).
In the other regions mentioned above, FDR-corrected p -values showed a trend toward significance ( p FDR ≤ 0.1; see Supplementary Table 2 ).
Discussion The current study suggests that patients who suffer from an AJCC stage III low rectal cancer with LLN+ have a worse LRFS and DFS, both showing a trend toward significance compared to similarly staged LLN− patients.
Although a trend toward significance was observed, the sample was underpowered to detect a definitive association.
Other cognitive improvements post-treatment in domains such as attention/executive function, verbal memory and learning, and psychomotor/visuospatial memory showed a trend toward significance, but this is likely owed to a large heterogeneity within the population.
All hypothesis tests were two-sided, and we defined P<0.05 as statistically significant and P<0.10 as a trend toward significance.
The results indicate a trend toward significance, but the evidence remains inconclusive.
After adjusting for the same five covariates, an increased plasma ACE level demonstrated a trend toward significance with the homozygous +9 patients ( Fig. 2 ).
Th statistical significance was set at p < 0.05, and a trend toward significance was considered at 0.05 ≤ p < 0.10. 3.
No significant differences were measured between 7 DPI and 28 DPI for both OFT and glutamate neurotransmission, however, a trend toward significance was observed over time post-injury.
However, transfusion volume and rate in the triple-dose group were lower than those in the single-dose group with a trend toward significance in transfusion reduction.
For all statistical tests, P < 0.05 was considered significant, whereas P < 0.1 was considered a trend toward significance.
However, multiple perioperative variables demonstrated an increased odds ratio of developing major postoperative complications that showed a trend toward significance.
However, even though the efficiency of the MPP8 KD was not very high, a trend toward significance showing upregulation of minor and major satellites and LINE repeats upon MPP8 KD was observed, in accordance with our RNA-Seq data.
Group analyses demonstrated a statistically significant poorer performance of children later diagnosed with dyslexia on the measure of RT discrimination at the pre-reading phase, while a trend toward significance was observed for RT discrimination in first and second grade.
It is noteworthy that over time with successive donations the Hb decreased as well, such that the proportion of female donors with values below 12.5 g/dL, increased from 11% to 25%, while the men has a trend toward significance, with an increase from 1% to 5%.
However, the latter showed a trend toward significance in the adjusted model, suggesting a potential positive influence of health education.