“a strong trend”

Although the statistical significance was borderline ( p = 0.056), this result indicates a strong trend toward increased Ni sensitivity in patients with CTD [ 312 ].

As expected, we observed a strong trend toward reduced hepatic triglyceride levels in the HFD-fed Pde9a −/− mice ( Fig. 5 I ), with minor differences in fatty acid composition between genotypes ( Supplementary Table 3 ).

Recent meta-analytic reanalysis of this study, however, demonstrated a prophylactic effect of LI plus OXC, with a strong trend not only toward prevention of new depressive episode (RR 0.294, 95% CI 0.086–1.002) but also against new manic, hypomanic, or mixed episodes (RR 0.301, 95% CI 0.101–0.899) [ 74 ].

Although not significant, we observed a strong trend towards reduction of LV mass index also in the medically treated group, with a median follow-up time of less than two years.

Only the slopes for the DEA-2.0 group were significantly more negative than the control group ( p = .016), and this was due to a strong trend observed in one subject.

Enhanced cortical expression of VGLUT3 and xCT along with a strong trend towards increased cortical extracellular glutamate levels have been reported elsewhere [ 41 ].

We describe a strong trend to lower [GSH] in males than in females on DOL 5, but we note that sexes were unbalanced in our cohort, with twice as many males as females, reducing our ability to accurately evaluate sex differences.

Previous study reported that pSS patients had a strong trend to present dyslipidemia when compared to healthy individuals ( Cruz et al., 2010 ).

However, systolic, diastolic and mean arterial pressures were higher in the women than the men, and HR showed a strong trend toward higher values in the women.

In the Th2 comparative AHC analysis, for successively more restrictive subsets of the DeepRNA-Reg prediction set based on a cut-off for the DBE percentile, there is a strong trend of greater enrichment of seed binding sequence motifs for miRNAs 23, 24, and 27 ( Figure 3(D) ).

Preliminary results demonstrate increased ATP or adenosine in specific brain regions [ 127 , 143 ], including a significant increase in ATP and a strong trend toward increased adenosine in cerebral cortex [ 127 ], and upregulated ATP synthase gene expression in hippocampus [ 20 , 141 ].

They concluded a strong trend of digitization, such as the application of information technology in the public health response to COVID-19 [ 17 ], and blockchain-based patient-centric data management system for managing electronic health records in cancer nursing [ 18 ].

However, there is a strong trend in previous literature in the professional field of social educators that has long contemplated the great challenge of incorporating this in educational centers (Machalík, 2020 ; Díez-Gutiérrez and Muñiz-Cortijo, 2022 ).

Enrollment was expanded beyond the originally planned 100 patients based on the probability of improved efficacy for time to recurrence of <0.95 and >0.70 (this range of probabilities represents a strong trend, i.e., not yet definitive) and if an estimate of increased time to recurrence and mortality exceeded 2 months during enrollment.

5 Conclusions and outlooks Metasurface and AI, as the cutting-edge research directions in the fields of optics and computer science in the 21st century, have demonstrated a strong trend of interdisciplinary integration.

Although we were not able to perform statistical analysis, there was a strong trend in that for each individual sample there was an increased transmigration of HIV + PBMC, suggesting their preferential transmigration across the BBB.

Effect of Ethanol on Enzymatic Activity Ethanol inhibition is a strong trend in the study of certain enzymes, since they can be exposed to substantial concentrations of alcohol for various industrial applications [ 6 ].

We noticed a strong trend for siRNA enrichment in gene flanking regions near transcription start sites (TSS) and transcription termination sites (TTS) (Figure 4D ).

3 , RCS showed a strong trend toward non-linear positive association of RC, Lp(a), and hsCRP with MACEs in our patients.

In soil, fungal richness and diversity had a strong trend towards being higher in conventional plots, whereas bacterial richness was more varied across samples.

The plasma levels of VEGF-A were significantly elevated in cystitis patients and there was a strong trend for significant overexpression in urine.

However, a strong trend was evident in that transposon copies with high mRNA expression in gametes tended to have fewer 24-nt siRNAs and vice versa ( Supplemental Fig.

In the second approach, MDA‐MB‐231 cells had a strong trend toward lower Ki67 staining at all doses.

However, with 44% (32/73), there is a strong trend toward the use of hybrid recommender techniques.

In our work, the agreement ranged between 83.3 and 100%, indicating a strong trend amongst the African health care professionals to have a treat-to-target approach for osteoporosis management.