While the difference in reactivity to K5Me2 between SLE patients with high and low IFN signatures did not reach statistical significance by ELISA, there was still a strong trend toward greater reactivity in patients who had high IFN signatures.
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p=0.077
In the literature
a strong trendgold
Randomized and registry evidence supports the selective use of ECMO in severe respiratory failure: the CESAR trial showed improved survival without severe disability at 6 months in patients referred to an ECMO center; EOLIA, while underpowered for its primary endpoint, demonstrated a strong trend toward lower 60-day mortality with early VV-ECMO and permitted crossover rescue.
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More stomach-content samples were available from winter than from the other seasons ( Figure 2 ), but the distribution of food types eaten by sandy inland mice did not differ between the seasons (χ 2 = 3.24, 6 df, p = 0.78) or boom-and-bust conditions (χ 2 = 5.94, 2 df, p = 0.051), although there was a strong trend for association in the latter test due to an increase in representation of invertebrates in the diet during busts ( Table 2 ).
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However, we did observe a strong trend.
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Furthermore, a strong trend of using machine learning methods is observed, with more than half of the studies presenting some form of machine learning in their solutions, with the prevalent use of supervised learning (101 articles).
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Additionally, Model 2 indicated that the combined influence of parent and peer support positively impacted self-concept scores, whereas the other models did not show a strong trend in either direction.
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In contrast, lung metastases grew slowest in mice treated with SAR405, with a strong trend toward reduced endpoint tumor burden in mice treated with SAR405 alone as compared to MBC-613, and the addition of SAR405 to MCB-613 restored efficacy to near levels observed for single-agent SAR405 ( Fig. 6 A and B ).
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For instance, CTLA-4 inhibitors were associated with a higher incidence of colitis and diarrhea, while PD-1 inhibitors showed a strong trend toward immune-related AEs, again, congruent with the current literature [ 29 , 30 ].
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There seems to be a strong trend, however, and our study may have been underpowered to find a significant difference.
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There was a strong trend toward a reduced mortality in the baricitinib group compared to the tocilizumab group, significant reduction of progression to mechanical ventilation and a significant shorter length of stay of survivors (for details see supplemental Table 1 ).
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Furthermore, we observed a robust induction of sox9b in adult fish, with expression increased more than twofold in the heart (2.40±0.565) and muscle (2.57±0.151) tissues, while other tissues also showed a strong trend toward upregulation (Figure 8G ).
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bicolor fields Spearman’s rank correlation analyses revealed a significant negative correlation between soil depth and each alpha diversity metric (Faith’s phylogenetic diversity, Shannon’s entropy, and the observed features), indicating a strong trend of decreasing microbial diversity with depth.
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We also observed a strong trend toward the collection of plant‐related quests by the students (Figure 3c,d ).
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Interestingly, KET affected only basal release in CMS-V, with a strong trend toward normalization, and no significant differences between CMS-V + KET group and CNT or CMS-R.
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Although the efficacy of BP 897 in acute or subacute schizophrenic patients was not demonstrated in this study, probably related to a low dose not reaching therapeutic levels, there was a strong trend toward an antipsychotic effect dependent on plasma exposure, supporting the hypothesis that a D 3 receptor antagonist or partial agonist could exhibit antipsychotic properties.
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In particular, there is a strong trend of increasing electronegativity from C to F which goes with a more negatively charged electrophilic central atom.
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Indicating a significant shift in the tobacco market and a strong trend towards alternatives to traditional smoking.
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In contrast, higher doses (10 8 ) resulted in a marked survival advantage, reaching statistical significance and showing a strong trend for 10 9 –10 10 CFU equivalent ( Figure 7 B).
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There was a strong trend for TS positive tumours having a poor prognosis, however, which is consistent with the published literature.
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Using this approach there appears to be a strong trend for higher Granger causality from the nucleus accumbens Core (NAcC) to all regions in WT rats, that was evident across all frequency bands.
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Although only the ND group had a significant reduction in sIgG4 level, the other two groups also showed a strong trend toward reduction when compared with the AR one ( Fig. 2A , B ).
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In addition, for patients with lagophthalmos, early eyelid weight placement lead to improvement in the change in overall FGS with a strong trend towards decreased ocular synkinesis and overall synkinesis when compared to those that did not have an eyelid weight.
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Author summary Recently there has been a strong trend for self-monitoring of your cardiovascular health and new wearable sport trackers and mobile applications are coming to the market everyday.
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In all five gene lists we observe a strong trend for ESC genes to have a very high average acetylation signal, i.e. the bars representing the gene sets all cluster on the right-hand side of the plot.
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showed a strong trend of preventing either AKI or delayed methotrexate elimination (>5 days), especially in males [ 6 ].